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Merck
CN

S2189

Sigma-Aldrich

SE 175

≥97%

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About This Item

经验公式(希尔记法):
C16H13NO6S
分子量:
347.34
MDL编号:
UNSPSC代码:
12352204
PubChem化学物质编号:
NACRES:
NA.77

质量水平

方案

≥97%

运输

wet ice

储存温度

−20°C

SMILES字符串

COC(=O)c1ccccc1SC(=O)c2ccc(CO[N+]([O-])=O)cc2

InChI

1S/C16H13NO6S/c1-22-15(18)13-4-2-3-5-14(13)24-16(19)12-8-6-11(7-9-12)10-23-17(20)21/h2-9H,10H2,1H3

InChI key

JDIVRBDMTYQVOK-UHFFFAOYSA-N

应用

SE 175 may be used in cell signaling studies.

生化/生理作用

An organic nitrate compound that acts as an NO donor in vivo following reductive transformation of the nitrate group to nitric oxide.
SE 175 is a nitrate compound that belongs to the same class as nitroglycerine. It acts as a vasodilator and has clinical use in the treatment of angina. NO donors also confer neuroprotection and relieve neuropathic pain.

储存分类代码

11 - Combustible Solids

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

个人防护装备

Eyeshields, Gloves, type N95 (US)


历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Gregory R J Thatcher et al.
Free radical biology & medicine, 37(8), 1122-1143 (2004-09-29)
Nitroglycerine has been used clinically in the treatment of angina for 130 years, yet important details on the mechanism of action, biotransformation, and the associated phenomenon of nitrate tolerance remain unanswered. The biological activity of organic nitrates can be said
Magda Rybczynska et al.
Vaccine, 38(33), 5337-5342 (2020-06-24)
Freezing of alum-based vaccines drastically alters their colloidal composition and leads to irreversible cluster formation. The loss of stability is well described, but the impact of frost damage on the functionality of the induced and secreted antibody repertoire has not

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