产品名称
S9 from Liver, Pooled, from rat(Sprague-Dawley), male
biological source
rat (Sprague-Dawley)
packaging
vial of ~20 mg
UniProt accession no.
shipped in
dry ice
storage temp.
−70°C
Quality Level
Gene Information
rat ... Mrps9(301371)
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Application
S9 from Liver, Pooled has been used in metabolic activation in Salmonella typhimurium strains.
Biochem/physiol Actions
Post-mitochondrial supernatant fraction from homogenized liver. Source of drug metabolizing enzymes including P-450, these pools are useful in the study of xenobiotic metabolism and drug interactions.
The hepatic S9 pools from a variety of biological sources represent the post-mitochondrial supernatant fraction from homogenized liver. Known to be a rich source of drug metabolizing enzymes including P-450, these pools are useful in the study of xenobiotic metabolism and drug interactions.
They are used in the Ames test, which is a method that uses bacteria to test if a given chemical causes mutations in the genetic material of a given test organism.
存储类别
10 - Combustible liquids
wgk
WGK 2
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)
法规信息
低风险生物材料
此项目有
Genotoxicity evaluation of locally produced dental porcelain-An in vitro study using the Ames and Comet assays
Noushad M, et al.
Toxicology in vitro, 23(6), 1145-1150 (2009)
Esra Erikel et al.
Environmental and molecular mutagenesis, 64(5), 291-308 (2023-05-10)
Amygdalin (AMY), a plant secondary metabolite containing nitrile, is a major component of the seeds of Rosaceae family plants. It is known that this compound has many pharmacological activities such as cancer prevention, antipyretic, and cough suppressant. In this study
The Ames Salmonella/microsome mutagenicity assay.
Mortelman K and Zeiger E
Mutation Research, 455(1-2), 29-60 (2000)
An improvement of the Ames test using a modified human liver S9 preparation.
Hakura A
Journal of Pharmacological and Toxicological Methods, 46(3), 169-172 (2001)
Leonara Fayer et al.
Toxicology research, 10(3), 511-522 (2021-06-19)
The titanium dioxide nanoparticles (NPs) have been applied to biomedical, pharmaceutical, and food additive fields. However, the effect on health and the environment are conflicting; thus, it has been reviewing several times. In this context, establishing standard robust protocols for
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Datasheet
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