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Merck
CN

S1885

Sigma-Aldrich

辛二酸双(N-羟基琥珀酰亚胺酯)

≥95%, powder

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别名:
辛二酸二琥珀酰亚胺酯, 双琥珀酰亚胺辛二酸酯, 辛二酸二琥珀酰亚胺酯 (DSS)
经验公式(希尔记法):
C16H20N2O8
CAS号:
分子量:
368.34
MDL编号:
UNSPSC代码:
12352100
PubChem化学物质编号:
NACRES:
NA.21

质量水平

检测方案

≥95%

形式

powder

反应适用性

reagent type: cross-linking reagent

溶解性

chloroform: 50 mg/mL
DMF: soluble
aqueous buffer: slightly soluble (may require 5-10% organic solvent in coupling mixture.)

储存温度

2-8°C

SMILES字符串

O=C(CCCCCCC(=O)ON1C(=O)CCC1=O)ON2C(=O)CCC2=O

InChI

1S/C16H20N2O8/c19-11-7-8-12(20)17(11)25-15(23)5-3-1-2-4-6-16(24)26-18-13(21)9-10-14(18)22/h1-10H2

InChI key

ZWIBGKZDAWNIFC-UHFFFAOYSA-N

一般描述

辛二酸双(N-羟基琥珀酰亚胺酯)是具有胺反应性的同源双官能交联剂。通常与含有伯胺的分子,在 pH 7.5(6.5-8.5)的缓冲液中通过酰胺键偶联。辛二酸双(N-羟基琥珀酰亚胺酯)结合8原子连接体。

应用

辛二酸双(N-羟基琥珀酰亚胺酯)用于:
  • 对细胞裂解缓冲液进行补充,用于免疫沉淀
  • 将寡核苷酸标准品与明胶缀合
  • 交联ASC(凋亡相关斑点样蛋白,含胱天蛋白酶募集结构域)寡聚体

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

个人防护装备

Eyeshields, Gloves, type N95 (US)


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