Monoclonal Anti-L-Selectin (CD62L) antibody produced in mouse

Recognizes the CD62L (L-Selectin, LAM-1, Leu8, TQ1, LECAM-1, LECCAM-1, DREG) surface antigen. The antibody recognizes an epitope localized to the lectin domain. It inhibits "rolling" interactions and significantly reduces the binding of FITC-yeast phosphomannan monoester core polysaccharide to lymphocytes, monocytes and neutrophils.
5^th Workshop: Code No. S061

human PHA-activated peripheral blood mononuclear cells.

CD62L, a glycoprotein and member of the selectin family of adhesion receptors, is constitutively expressed on all classes of leukocytes including lymphocytes, monocytes, and polymorphonuclear cells. It is expressed on myeloid progenitor cells, erythroid precursor cells, and some thymocytes.

Solution, 0.2 μm filtered, in 0.01 M phosphate buffered saline, pH 7.4.

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