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Merck
CN

S1172

Anti-Syntaxin 1 antibody produced in rabbit

IgG fraction of antiserum, lyophilized powder

别名:

Anti-GEFSP9, Anti-STX1B1, Anti-STX1B2

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UNSPSC Code:
12352203
NACRES:
NA.41
MDL number:
MFCD00164742

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产品名称

Anti-Syntaxin 1 antibody produced in rabbit, IgG fraction of antiserum, lyophilized powder

biological source

rabbit

conjugate

unconjugated

antibody form

IgG fraction of antiserum

antibody product type

primary antibodies

clone

polyclonal

form

lyophilized powder

species reactivity

mouse, rat

technique(s)

immunohistochemistry: suitable using rat brain sections
western blot (chemiluminescent): 1:1,000 using rat brain membranes

UniProt accession no.

P61266

storage temp.

−20°C

target post-translational modification

unmodified

Quality Level

100

Gene Information

mouse ... Stx1a(20907), Stx1b(56216)
rat ... Stx1a(116470), Stx1b(24923)

Application

Anti-Syntaxin 1 antibody has been used in western blotting and immunohistochemistry.

Biochem/physiol Actions

Syntaxin 1 (STX1A) may control exocytosis in synaptic vesicles. In retina, STX1A may help in the structural formation of the INL (inner nuclear layer) and OPL(outer plexiform layer). Deletion of STX1A in mice affects the functions of hypothalamic-pituitary-adrenal axis. It may participate in spinal nociceptive plasticity promoted by peripheral nerve injury.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

General description

Syntaxin 1 is a membrane protein. It is also known as HPC-1. Neurons express syntaxin 1A.

Immunogen

highly purified GST fusion protein with the residues 1-265 of rat syntaxin 1A (intracellular, N-terminal).

Physical form

After reconstitution, the antibody solution is phosphate buffered saline, pH 7.4, containing 1% BSA and 0.05% sodium azide.

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pictograms

Exclamation mark
GHS07

signalword

Warning

Hazard Classifications

Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Aquatic Chronic 3

存储类别

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

法规信息

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历史批次信息供参考:

分析证书(COA)

Lot/Batch Number
SLCM7085
MKCQ3751
SLCH6329
SLCK3441
SLCK8653

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A Critical role for Bim in retinal ganglion cell death
McKernan DP and Cotter TG
Journal of Neurochemistry, 102(3), 922-930 (2007)
Syntaxin 1 is expressed in the trout saccular hair cells: RT-PCR and immunocytochemical observations
KM Khan, et al.
Iranian Journal of Pharmaceutical Research : IJPR, 3, 10-10 (2004)
Tiziana Cotrufo et al.
The European journal of neuroscience, 36(9), 3152-3164 (2012-09-06)
Directed cell migration and axonal guidance are essential steps in neural development that share many molecular mechanisms. The guidance of developing axons and migrating neurons is likely to depend on the precise control of plasmalemma turnover in selected regions of
SNARE protein expression in synaptic terminals and astrocytes in the adult hippocampus: a comparative analysis
Schubert V, et al.
Glia, 59(10), 1472-1488 (2011)
Chronic exercise enhances insulin secretion ability of pancreatic islets without change in insulin content in non-diabetic rats
Tsuchiya M, et al.
Biochemical and Biophysical Research Communications, 430(2), 676-682 (2013)
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