推荐产品
生物来源
rabbit
质量水平
偶联物
unconjugated
抗体形式
IgG fraction of antiserum
抗体产品类型
primary antibodies
克隆
polyclonal
形式
lyophilized powder
种属反应性
mouse, rat
技术
immunohistochemistry: suitable using rat brain sections
western blot (chemiluminescent): 1:1,000 using rat brain membranes
UniProt登记号
储存温度
−20°C
基因信息
mouse ... Stx1a(20907) , Stx1b(56216)
rat ... Stx1a(116470) , Stx1b(24923)
一般描述
Syntaxin 1 is a membrane protein. It is also known as HPC-1. Neurons express syntaxin 1A.
免疫原
highly purified GST fusion protein with the residues 1-265 of rat syntaxin 1A (intracellular, N-terminal).
应用
Anti-Syntaxin 1 antibody has been used in western blotting and immunohistochemistry.
生化/生理作用
Syntaxin 1 (STX1A) may control exocytosis in synaptic vesicles. In retina, STX1A may help in the structural formation of the INL (inner nuclear layer) and OPL(outer plexiform layer). Deletion of STX1A in mice affects the functions of hypothalamic-pituitary-adrenal axis. It may participate in spinal nociceptive plasticity promoted by peripheral nerve injury.
外形
After reconstitution, the antibody solution is phosphate buffered saline, pH 7.4, containing 1% BSA and 0.05% sodium azide.
免责声明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
警示用语：
Warning
危险声明
危险分类
Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Aquatic Chronic 3
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
Eyeshields, Gloves, type N95 (US)
法规信息
常规特殊物品
含少量动物源组分生物产品
A Critical role for Bim in retinal ganglion cell death
McKernan DP and Cotter TG
Journal of Neurochemistry, 102(3), 922-930 (2007)
Impaired NGF/TrkA Signaling Causes Early AD-Linked Presynaptic Dysfunction in Cholinergic Primary Neurons
Latina V, et al.
Frontiers in Cellular Neuroscience, 11 (2017)
SNARE protein expression in synaptic terminals and astrocytes in the adult hippocampus: a comparative analysis
Schubert V, et al.
Glia, 59(10), 1472-1488 (2011)
Syntaxin 1 is expressed in the trout saccular hair cells: RT-PCR and immunocytochemical observations
KM Khan, et al.
Iranian Journal of Pharmaceutical Research : IJPR, 3, 10-10 (2004)
Tiziana Cotrufo et al.
The European journal of neuroscience, 36(9), 3152-3164 (2012-09-06)
Directed cell migration and axonal guidance are essential steps in neural development that share many molecular mechanisms. The guidance of developing axons and migrating neurons is likely to depend on the precise control of plasmalemma turnover in selected regions of
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