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Merck
CN

S1140

Sigma-Aldrich

Anti-Sheep IgG (whole molecule) antibody produced in rabbit

whole antiserum

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MDL编号:
UNSPSC代码:
12352203
NACRES:
NA.46

生物来源

rabbit

质量水平

偶联物

unconjugated

抗体形式

whole antiserum

抗体产品类型

secondary antibodies

克隆

polyclonal

包含

15 mM sodium azide

技术

indirect ELISA: 1:100,000
quantitative precipitin assay: 2.8-4.2 mg/mL

运输

dry ice

储存温度

−20°C

靶向翻译后修饰

unmodified

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相关类别

一般描述

Immunoglobulin G (IgG) belongs to the immunoglobulin family and is a widely expressed serum antibody. An immunoglobulin has two heavy chains and two light chains connected by a disulfide bond. IgG is a major class of immunoglobulin. Immunoglobulin molecules of sheep are of the λ type.

特异性

The antiserum is determined to be immunospecific for sheep IgG

应用

Anti-Sheep IgG (whole molecule) antibody produced in rabbit has been used in radioimmunoassay.

生化/生理作用

IgG antibody subtype is the most abundant of serum immunoglobulins of the immune system. It is secreted by B cells and is found in blood and extracellular fluids and provides protection from infections caused by bacteria, fungi and viruses. Maternal IgG is transferred to fetus through the placenta that is vital for immune defense of the neonate against infections.
Immunoglobulin G (IgG) participates in hypersensitivity type II and type III. It is a glycoprotein and mainly helps in immune defense.

外形

Supplied as a liquid containing 15 mM sodium azide as preservative.

制备说明

treated to remove lipoproteins

储存及稳定性

For continuous use, store at 2-8 °C for up to one month. For extended storage, the solution may be frozen in working aliquots. Repeated freezing and thawing, or storage in "frost-free" freezers, is notrecommended. If slight turbidity occurs upon prolonged storage, clarify the solution by centrifugation before use.

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

个人防护装备

Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter

法规信息

常规特殊物品

分析证书(COA)

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Specific IgG for cat allergens in patients with allergic conjunctivitis
Miyama A, et al.
International Ophthalmology, 35, 575-586 (2015)
J B Richards et al.
Theriogenology, 52(6), 1055-1066 (2000-03-29)
Sixteen ram lambs (5 m.o. old, 45 +/- 1.5 kg) received a control diet (50% concentrate, no locoweed, n = 4), locoweed (20% locoweed for 21 d, n = 4), MUSE (2 mL i.m. of MUSE containing 5 mg selenium
Antibody structure, instability, and formulation.
Wang W
Journal of Pharmaceutical Sciences, 96(1), 1-26 (2007)
S Hashira et al.
Pediatrics international : official journal of the Japan Pediatric Society, 42(4), 337-342 (2000-09-15)
Maternal immunoglobulin G (IgG), transferred across the placenta to the fetus during intrauterine life, is an important component of the neonatal immunological defence mechanisms against infection. There is controversy with respect to differences in placental transfer of the different IgG

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