跳转至内容
Merck
CN
所有图片(3)

文件

S0756

Sigma-Aldrich

鞘髓磷脂

from chicken egg yolk, ≥95%

登录查看公司和协议定价
所有图片(3)
别名:
N-Acyl-4-sphingenyl-1-O-phosphorylcholine, N-酰基-D-鞘氨醇-1-磷酸胆碱
CAS号:
85187-10-6
EC 号:
286-097-2
MDL编号:
MFCD00132361
UNSPSC代码:
12352211
NACRES:
NA.25

生物来源

chicken egg yolk

质量水平

200

检测方案

≥95%

形式

powder

溶解性

chloroform/methanol: soluble 50 mg/mL, clear, colorless to faintly yellow (1:1)

官能团

phospholipid

脂质类型

sphingolipids

运输

ambient

储存温度

−20°C

SMILES字符串

CCCCCCCCCCCCC/C=C/[C@H]([C@@H](NC=O)COP(O)(OCC[N+](C)(C)C)=O)O

InChI

1S/C24H49N2O6P/c1-5-6-7-8-9-10-11-12-13-14-15-16-17-18-24(28)23(25-22-27)21-32-33(29,30)31-20-19-26(2,3)4/h17-18,22-24,28H,5-16,19-21H2,1-4H3,(H-,25,27,29,30)/p+1/b18-17+/t23-,24+/m0/s1

InChI key

LRYZPFWEZHSTHD-HEFFAWAOSA-O

正在寻找类似产品? 访问 产品对比指南

一般描述

鞘磷脂（SM）是哺乳动物细胞膜中的主要鞘脂。已经研究了它的生物学功能。

应用

鞘磷脂适合使用：
  • 在酶法测定血浆鞘磷脂水平的标准制备品中
  • 研究血管抗凝血剂 α（VAC α）与平面磷脂双分子层的结合
  • 对联合超声处理的卵磷脂和鞘磷脂的分散体中的 PC16（N- [α-N-棕榈酰-ε-N-（4-硝基苯并-2-氧杂-1，3-二唑）-L-赖氨酸] -2-氨基乙醇-N-（三甲基氨基乙醇）磷酸盐）的进行荧光偏振
  • 用于将病毒离子通道蛋白 M2 重建成脂质体
  • 作为使用飞行时间二次离子质谱（ToF-SIMS）定义光谱指纹的标准样品
  • 评估各种磷脂对羊水中泡沫形成的贡献

生化/生理作用

鞘磷脂是 HDL 和质膜中第二丰富的脂质和主要的鞘脂成分。它形成富含胆固醇的脂筏。它在无质膜胆固醇的可用性中起关键作用。

质量

主要含有棕榈酸。

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

个人防护装备

Eyeshields, Gloves, type N95 (US)

分析证书(COA)

输入产品批号来搜索 分析证书(COA) 。批号可以在产品标签上"批“ （Lot或Batch）字后找到。

已有该产品？

在文件库中查找您最近购买产品的文档。

访问文档库

Biological functions of sphingomyelins.
Slotte JP.
Progress in Lipid Research, 52(4), 424-437 (2013)
H A Andree et al.
The Journal of biological chemistry, 265(9), 4923-4928 (1990-03-25)
Vascular anticoagulant alpha (VAC alpha, annexin V) is a member of the family of calcium and phospholipid binding proteins, the annexins. The binding properties of VAC alpha to phospholipid bilayers were studied by ellipsometry. Adsorption was calcium-dependent and completely reversible
J C Russell
Clinical chemistry, 33(7), 1177-1184 (1987-07-01)
The mechanism of a new fluorescence polarization method for measuring phospholipid in amniotic fluid is described. The fluorescence polarization of a surfactant fluorescent dye solubilized in amniotic fluid correlates significantly with the L/S ratio. Model studies indicate that this results
S Fiorucci et al.
Gut, 38(2), 182-189 (1996-02-01)
The tumour necrosis factor alpha (TNF), has been implicated in the pathogenesis of non-steroidal anti-inflammatory drug (NSAID) induced gastropathy and Helicobacter pylori induced gastritis. Both conditions are characterised by high plasma pepsinogen concentrations, which are thought to reflect an increased
Mohammad Reza Hojjati et al.
Journal of lipid research, 47(3), 673-676 (2005-12-24)
Sphingomyelin (SM) and phosphatidylcholine (PC) are two major phospholipids on plasma lipoproteins. Their concentration is classically measured by lipid extraction, thin-layer chromatography, and phosphate determination on separated SM or PC spots. Here, we describe two rapid, specific, and sensitive enzymatic
查看所有相关文献

实验方案

LC/MS Analysis of Phospholipids in Milk on Asc

(soybean), ≥97%; L-α-Phosphatidylethanolamine from egg yolk, Type III, ≥97% (TLC), lyophilized powder; L-α-Phosphatidylcholine, from egg yolk, Type XVI-E, ≥99% (TLC), lyophilized powder; Sphingomyelin, from chicken egg yolk, ≥95%

我们的科学家团队拥有各种研究领域经验，包括生命科学、材料科学、化学合成、色谱、分析及许多其他领域.

联系技术服务部门