生物来源
rabbit
质量水平
偶联物
unconjugated
抗体形式
affinity isolated antibody
抗体产品类型
primary antibodies
克隆
polyclonal
形式
buffered aqueous solution
种属反应性
human
存货情况
not available in Japan
技术
immunohistochemistry (formalin-fixed, paraffin-embedded sections): 24 μg/mL using human pancreas, Islets of Langerhans (Optimal dilution should be determined by the researcher.)
UniProt登记号
运输
dry ice
储存温度
−70°C
基因信息
human ... SSTR2(6752)
mouse ... Sstr2(20606)
rat ... Sstr2(54305)
一般描述
Somatostatin receptor 2 (SSTR2) is encoded by the gene mapped to human chromosome 17q25.1. It is mainly localized on choroid plexus and arachnoid granulations. SSTR2 is transcribed into two isoforms, SSTR2A and SSTR2B through alternative splicing.
免疫原
synthetic peptide corresponding to the second extracellular loop of human somatostatin receptor type 2, conjugated to KLH. The immunizing peptide has 100% homology with the rat and mouse gene.
生化/生理作用
Somatostatin receptor 2 (SSTR2) mediates human anterior pituitary hormone suppression by interacting with its peptide ligand somatostatin. It also plays a major role in maintenance of brain fluid homeostasis. The encoded protein has an ability to hinder the cell proliferation of solid tumors. Experimental studies states that SSTR2 methylation is presumed to be involved in the metastasis and invasion of laryngeal cancer.
外形
Solution in phosphate buffered saline, pH 7.7, containing 0.1% sodium azide.
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WGK
nwg
闪点(°F)
Not applicable
闪点(°C)
Not applicable
法规信息
新产品
Genetic analysis of inherited hydrocephalus in a rat model
Jones HC, et al.
Experimental Neurology, 190, 79-90 (2004)
SSTR2 promoter hypermethylation is associated with the risk and progression of laryngeal squamous cell carcinoma in males
Shen Z, et al.
Diagnostic Pathology (2016)
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