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Merck
CN

S0202

Sigma-Aldrich

异豆香脂素二葡萄糖苷

≥97% (HPLC)

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别名:
SDG
经验公式(希尔记法):
C32H46O16
分子量:
686.70
UNSPSC代码:
12352205
NACRES:
NA.25

质量水平

检测方案

≥97% (HPLC)

形式

powder

储存条件

protect from light

颜色

white to off-white

溶解性

H2O: 1 mg/mL, clear, colorless

应用

metabolomics
vitamins, nutraceuticals, and natural products

储存温度

2-8°C

InChI

1S/C20H26O6.C6H12O6/c1-25-19-9-13(3-5-17(19)23)7-15(11-21)16(12-22)8-14-4-6-18(24)20(10-14)26-2;7-1-2-3(8)4(9)5(10)6(11)12-2/h3-6,9-10,15-16,21-24H,7-8,11-12H2,1-2H3;2-11H,1H2/t15-,16-;2-,3-,4+,5-,6-/m01/s1

InChI key

MJYQFWSXKFLTAY-OVEQLNGDSA-N

一般描述

亚麻木酚素(SDG)是亚麻籽中的一种必需的膳食木脂素。它具有寡聚体结构。

应用


  • Supplementing flaxseed meal with sucrose, flaxseed oil, or both: Effect on milk enterolactone, ruminal microbiota profile, production performance, and nutrient utilization in dairy cows.: This study explores the effects of secoisolariciresinol diglucoside (SDG) from flaxseed meal on milk production, enterolactone levels, and the ruminal microbiota profile in dairy cows, highlighting its role in improving nutrient utilization and production performance (Ghedini CP et al., 2024).

  • Successful Outcome of a Patient with Concomitant Pancreatic and Renal Carcinoma Receiving Secoisolariciresinol Diglucoside Therapy Alone: A Case Report.: This case report documents a patient with pancreatic and renal carcinoma treated solely with SDG, showcasing its potential therapeutic effects in oncology and highlighting a novel application in cancer treatment (Wu H et al., 2024).

  • Linagliptin and secoisolariciresinol diglucoside attenuate hyperlipidemia and cardiac hypertrophy induced by a high-methionine diet in rats via suppression of hyperhomocysteinemia-induced endoplasmic reticulum stress.: This study demonstrates the combined therapeutic effects of SDG and linagliptin in reducing hyperlipidemia and cardiac hypertrophy, highlighting its potential in cardiovascular health applications (Jalal IA et al., 2023).

生化/生理作用

亚麻木酚素(SDG)是一种金属螯合配体,对乳腺癌细胞有抗增殖和促凋亡作用。它对镉诱导的大鼠肾毒性具有肾脏保护作用。SDG 是一种强效抗炎剂,可防止血脑屏障与炎症细胞的相互作用,并预防神经炎性疾病。它还是一种良好的抗糖尿病剂。
开环异落叶松树脂酚二葡萄糖苷是存在于亚麻、向日葵、芝麻和南瓜种子中的一种植物化学物质。它是哺乳动物木脂素和植物雌激素的一种前体。开环异落叶松树脂酚二葡萄糖苷已被证明具有抗氧化和心脏保护作用。

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable


分析证书(COA)

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Thomas J Schmidt et al.
Phytochemistry, 82, 89-99 (2012-08-03)
Mature seeds of 20 Linum species were analyzed for their content of lignans. The seeds of common flax (Linum usitatissimum L.) are known to contain as characteristic lignan sesoisolariciresinol diglucoside (SDG), whose presence in seeds of some other Linum species
Márcia Constantino Colli et al.
Journal of medicinal food, 15(9), 840-845 (2012-08-29)
The objective of this study was to evaluate the efficacy of flaxseed meal and flaxseed extract in reducing climacteric symptoms of menopausal women. Ninety menopausal women were randomly distributed into three study groups: group I received 1 g per day of
Alexander M Scherbakov et al.
Natural product research, 35(24), 6099-6105 (2020-10-08)
Secoisolariciresinol diglucoside (SDG) is isolated from Linum usitatissimum seeds. The antiproliferative effects of SDG (1) and its derivatives secoisolariciresinol (2) and secoisolariciresinol-4', 4″-diacetate (3) have been evaluated on MCF-7 breast cancer cells and normal breast epithelial line MCF-10A. Lignan 1
Sadiq S Moree et al.
Phytomedicine : international journal of phytotherapy and phytopharmacology, 20(3-4), 237-245 (2012-12-29)
Diabetes mellitus is a chronic metabolic disorder characterized by hyperglycaemia. Its complications such as neuropathy, cardiopathy, nephropathy, and micro and macro vascular diseases are believed to be due to the increase in oxidative stress and decrease in the level of
Melpo Christofidou-Solomidou et al.
Radiation research, 178(6), 568-580 (2012-10-31)
While dietary wholegrain Flaxseed (FS) has potent anti-inflammatory, anti-fibrotic and antioxidant properties in murine models of acute and chronic lung injury, the main bioactive ingredient that contributes to these protective effects remains unknown. This study evaluated the lignan complex of

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