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生物来源
mouse
质量水平
重组
expressed in E. coli
方案
≥97% (SDS-PAGE)
表单
lyophilized powder
效能
0.4-3.0 μg/mL ED50
分子量
predicted mol wt 20 kDa
包装
pkg of 25 μg
储存条件
avoid repeated freeze/thaw cycles
杂质
<1 EU/μg
UniProt登记号
储存温度
−20°C
基因信息
mouse ... Shh(20423)
一般描述
Sonic hedgehog (Shh) is a morphogenic glycoprotein. The gene encoding it is localized on mouse chromosome 5.
应用
Sonic hedgehog peptide from mouse has been used for neural differentiation.
生化/生理作用
Cell signaling peptide involved in embryonic morphogenic development of several tissues including Hensen′s node, the notochord, and the neural tube.
Involved in embryonic morphogenic development of several tissues including Hensen′s node, the notochord, and the neural tube.
Sonic hedgehog (Shh) has a role in fracture healing and regeneration. The protein associates with its receptor Patched (Ptc-1), de-represses Smoothened (Smo) and activates the Gli family of transcription factors. Mutations in the Shh pathway have been linked to developmental diseases and cancer.
其他说明
N-terminal peptide encoding amino acid residues 25-198.
外形
Lyophilized from a 0.2 μm filtered solution in phosphate buffered saline, pH 7.4, containing 5% trehalose and 50 μg of bovine serum albumin per 1 μg of cytokine.
储存分类代码
11 - Combustible Solids
WGK
WGK 2
闪点(°F)
Not applicable
闪点(°C)
Not applicable
法规信息
含少量动物源组分生物产品
常规特殊物品
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Berretta A
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