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种属反应性
human
技术
ELISA: suitable
输入
sample type plasma
sample type cell culture supernatant(s)
sample type serum
assay range
inter-assay cv: <12%
intra-assay cv: <10%
运输
wet ice
储存温度
−20°C
基因信息
human ... CHL1(10752)
一般描述
CHL1 (cell adhesion molecule L1 like) gene codes for a cell-adhesion molecule. It belongs to the L1 family of cell adhesion molecules. The CHL1gene is mapped to human chromosome 3p26.
This ELISA antibody pair detects Human Cell Adhesion Molecule with Homology to L1CAM (L1CAM-2)
应用
For research use only. Not for use in diagnostic procedures.
Please refer to the attached Protocolfor details.
Please refer to the attached Protocolfor details.
生化/生理作用
The axon guidance protein encoded by CHL1 (cell adhesion molecule L1 like) gene plays a major role in the guidance of thalamocortical axons and the multiplication and differentiation of neural progenitor cells. CHL1 acts as a tumor-suppressor gene in breast cancer (BC). Mutation in the axon guidance protein results in horizontal gaze palsy with progressive scoliosis (HGPPS). It participates in mental development.
其他说明
A sample Certificate of Analysis is available for this product. Please type the word sample in the text box provided for lot number.
警示用语：
Warning
危险声明
预防措施声明
危险分类
Met. Corr. 1
储存分类代码
8A - Combustible corrosive hazardous materials
闪点(°F)
Not applicable
闪点(°C)
Not applicable
法规信息
新产品
Microarray based analysis of an inherited terminal 3p26.3 deletion, containing only the CHL1 gene, from a normal father to his two affected children
Cuoco C et al.
Orphanet Journal of Rare Diseases, 6(1), 12-12 (2011)
CHL1 hypermethylation as a potential biomarker of poor prognosis in breast cancer
Martin-Sanchez E, et al.
Oncotarget, 8(9), 15789-15789 (2017)
Lack of association between the CHL1 gene and adolescent idiopathic scoliosis susceptibility in Han Chinese: a case-control study
Qiu XS, et al.
BMC Musculoskelet. Disord., 15(1), 38-38 (2014)
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