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Merck
CN

RAB1365

Sigma-Aldrich

人CHL-1 ELISA

for serum, plasma and cell culture supernatants

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About This Item

UNSPSC代码:
41116158
NACRES:
NA.32

种属反应性

human

技术

ELISA: suitable

输入

sample type plasma
sample type cell culture supernatant(s)
sample type serum

assay range

inter-assay cv: <12%
intra-assay cv: <10%

运输

wet ice

储存温度

−20°C

基因信息

human ... CHL1(10752)

一般描述

CHL1 (cell adhesion molecule L1 like) gene codes for a cell-adhesion molecule. It belongs to the L1 family of cell adhesion molecules. The CHL1gene is mapped to human chromosome 3p26.
This ELISA antibody pair detects Human Cell Adhesion Molecule with Homology to L1CAM (L1CAM-2)

应用

For research use only. Not for use in diagnostic procedures.
Please refer to the attached Protocolfor details.

生化/生理作用

The axon guidance protein encoded by CHL1 (cell adhesion molecule L1 like) gene plays a major role in the guidance of thalamocortical axons and the multiplication and differentiation of neural progenitor cells. CHL1 acts as a tumor-suppressor gene in breast cancer (BC). Mutation in the axon guidance protein results in horizontal gaze palsy with progressive scoliosis (HGPPS). It participates in mental development.

其他说明

A sample Certificate of Analysis is available for this product. Please type the word sample in the text box provided for lot number.

象形图

Corrosion

警示用语:

Warning

危险声明

预防措施声明

危险分类

Met. Corr. 1

储存分类代码

8A - Combustible corrosive hazardous materials

闪点(°F)

Not applicable

闪点(°C)

Not applicable

法规信息

新产品

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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访问文档库

Microarray based analysis of an inherited terminal 3p26.3 deletion, containing only the CHL1 gene, from a normal father to his two affected children
Cuoco C et al.
Orphanet Journal of Rare Diseases, 6(1), 12-12 (2011)
CHL1 hypermethylation as a potential biomarker of poor prognosis in breast cancer
Martin-Sanchez E, et al.
Oncotarget, 8(9), 15789-15789 (2017)
Lack of association between the CHL1 gene and adolescent idiopathic scoliosis susceptibility in Han Chinese: a case-control study
Qiu XS, et al.
BMC Musculoskelet. Disord., 15(1), 38-38 (2014)

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