产品名称
大鼠脂联素 ELISA 试剂盒, for cell culture supernatants, plasma, and serum samples
species reactivity
rat
packaging
kit of 96 wells (12 strips x 8 wells)
technique(s)
ELISA: suitable
input
sample type cell culture supernatant(s)
sample type plasma
sample type serum sample(s)
assay range
inter-assay cv: <12%
intra-assay cv: <10%
sensitivity: 0.8 ng/ml
detection method
colorimetric
shipped in
wet ice
storage temp.
−20°C
Gene Information
rat ... Adipoq(246253)
Application
For research use only. Not for use in diagnostic procedures.
Please refer to the attached Protocolfor details.
Please refer to the attached Protocolfor details.
Biochem/physiol Actions
Adiponectin, also known as AdipoQ, is a plasma protein produced by adipocytes. Downregulation of adiponectin by mutation causes insulin resistance and type 2 diabetes. The expression level of adiponectin in plasma is lower in obesity. Adiponectin interacts with other proteins produced by adipocytes and is involved in triglyceride synthesis. Adiponectin in plasma lowers the expression of adhesion molecules in vascular endothelial cells and reduces the risk of atherogenic vascular diseases.
General description
This ELISA antibody pair detects Rat Adiponectin (ADIPOQ/ACRP30)
Other Notes
A sample Certificate of Analysis is available for this product. Please type the word sample in the text box provided for lot number.
signalword
Warning
hcodes
pcodes
Hazard Classifications
Met. Corr. 1
存储类别
8A - Combustible corrosive hazardous materials
flash_point_f
Not applicable
flash_point_c
Not applicable
法规信息
新产品
此项目有
Genomic structure and mutations in adipose-specific gene, adiponectin
Takahashi M, et al.
International journal of obesity (2005), 24(7), 861-868 (2000)
Association of adiponectin mutation with type 2 diabetes: a candidate gene for the insulin resistance syndrome
Kondo H, et al.
Diabetes, 51(7), 2325-2328 (2002)
Paradoxical decrease of an adipose-specific protein, adiponectin, in obesity
Arita Y, et al.
Biochemical and Biophysical Research Communications, 257(1), 79-83 (1999)
Jóctan Pimentel Cordeiro et al.
PloS one, 17(8), e0271592-e0271592 (2022-08-12)
There are evidence that obese-resistant animals are more physically active, due to a higher rate of lipid oxidation. Efficiency in such pathways can favor greater spontaneous physical activity and, consequently, less body fat deposition. The aim of study was characterizing
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