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种属反应性
rat
包装
kit of 96 wells (12 strips x 8 wells)
技术
ELISA: suitable
输入
sample type cell culture supernatant(s)
sample type plasma
sample type serum sample(s)
assay range
inter-assay cv: <12%
intra-assay cv: <10%
sensitivity: 0.8 ng/ml
检测方法
colorimetric
运输
wet ice
储存温度
−20°C
基因信息
rat ... Adipoq(246253)
一般描述
This ELISA antibody pair detects Rat Adiponectin (ADIPOQ/ACRP30)
应用
For research use only. Not for use in diagnostic procedures.
Please refer to the attached Protocolfor details.
Please refer to the attached Protocolfor details.
生化/生理作用
Adiponectin, also known as AdipoQ, is a plasma protein produced by adipocytes. Downregulation of adiponectin by mutation causes insulin resistance and type 2 diabetes. The expression level of adiponectin in plasma is lower in obesity. Adiponectin interacts with other proteins produced by adipocytes and is involved in triglyceride synthesis. Adiponectin in plasma lowers the expression of adhesion molecules in vascular endothelial cells and reduces the risk of atherogenic vascular diseases.
其他说明
A sample Certificate of Analysis is available for this product. Please type the word sample in the text box provided for lot number.
警示用语：
Warning
危险声明
预防措施声明
危险分类
Met. Corr. 1
储存分类代码
8A - Combustible corrosive hazardous materials
闪点(°F)
Not applicable
闪点(°C)
Not applicable
法规信息
新产品
Association of adiponectin mutation with type 2 diabetes: a candidate gene for the insulin resistance syndrome
Kondo H, et al.
Diabetes, 51(7), 2325-2328 (2002)
Genomic structure and mutations in adipose-specific gene, adiponectin
Takahashi M, et al.
International journal of obesity (2005), 24(7), 861-868 (2000)
Paradoxical decrease of an adipose-specific protein, adiponectin, in obesity
Arita Y, et al.
Biochemical and Biophysical Research Communications, 257(1), 79-83 (1999)
Jóctan Pimentel Cordeiro et al.
PloS one, 17(8), e0271592-e0271592 (2022-08-12)
There are evidence that obese-resistant animals are more physically active, due to a higher rate of lipid oxidation. Efficiency in such pathways can favor greater spontaneous physical activity and, consequently, less body fat deposition. The aim of study was characterizing
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