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Merck
CN
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主要文件

安全信息

RAB1091

Sigma-Aldrich

人TREM-2 ELISA试剂盒

for cell culture supernatants, plasma, and serum samples

别名:

TREM2, Triggering receptor expressed on myeloid cells 2

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About This Item

UNSPSC代码:
41116158
NACRES:
NA.84

种属反应性

human

包装

kit of 96 wells (12 strips x 8 wells)

技术

ELISA: suitable

输入

sample type serum sample(s)
sample type plasma
sample type cell culture supernatant(s)

assay range

inter-assay cv: <12%
intra-assay cv: <10%
sensitivity: 28 pg/ml

检测方法

colorimetric

运输

wet ice

储存温度

−20°C

基因信息

human ... TREM2(54209)

一般描述

This ELISA antibody pair detects human TREM-2. Other species not yet determined.

应用

For research use only. Not for use in diagnostic procedures.
Please refer to the attached Protocolfor details.

其他说明

A sample Certificate of Analysis is available for this product. Please type the word sample in the text box provided for lot number.

象形图

Corrosion

警示用语:

Warning

危险声明

预防措施声明

危险分类

Met. Corr. 1

储存分类代码

8A - Combustible corrosive hazardous materials

闪点(°F)

Not applicable

闪点(°C)

Not applicable

法规信息

新产品

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Weigang Cui et al.
Frontiers in neuroscience, 14, 444-444 (2020-06-09)
Accumulating evidence has indicated that activation of microglia and neuroinflammation reaction play a prominent role in Alzheimer's disease (AD). Inhibition of toll-like receptor 4 (TLR4) has been shown to be associated with immune responses and brain damage, but its effects
Takayuki Inoue et al.
Proceedings of the National Academy of Sciences of the United States of America, 116(20), 10031-10038 (2019-05-01)
Cerebral amyloid angiopathy (CAA) results from amyloid-β deposition in the cerebrovasculature. It is frequently accompanied by Alzheimer's disease and causes dementia. We recently demonstrated that in a mouse model of CAA, taxifolin improved cerebral blood flow, promoted amyloid-β removal from
Megan M Varnum et al.
The Journal of biological chemistry, 292(25), 10651-10663 (2017-05-12)
Triggering receptor expressed on myeloid cells 2 (TREM2) is a single transmembrane molecule uniquely expressed in microglia. TREM2 mutations are genetically linked to Nasu-Hakola disease and associated with multiple neurodegenerative disorders, including Alzheimer's disease. TREM2 may regulate microglial inflammation and

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