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Merck
CN

RAB1052

Sigma-Aldrich

人 GHRL/Ghrelin ELISA 试剂盒

for cell culture supernatants, plasma, and serum samples

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About This Item

UNSPSC代码:
41116158
NACRES:
NA.32

种属反应性

human

包装

kit of 96 wells (12 strips x 8 wells)

技术

ELISA: suitable

输入

sample type plasma
sample type serum sample(s)
sample type cell culture supernatant(s)

assay range

inter-assay cv: <12%
intra-assay cv: <10%
sensitivity: 8 pg/mL

检测方法

colorimetric

运输

wet ice

储存温度

−20°C

基因信息

human ... GHRL(51738)

一般描述

This ELISA antibody pair detects Human Ghrelin (GHRL)

应用

For research use only. Not for use in diagnostic procedures.
Please refer to the attached Protocolfor details.

生化/生理作用

The peptide ghrelin, one of the cleavage products of prepropeptide produced from the GHRL (growth hormone-releasing peptide) gene, functions in stimulating food intake and controlling energy balance. It has potent stimulating effects on the secretion of growth hormone. GHRL serves as an endogenous ligand for the growth hormone secretagogue receptor 1α (GHSR 1α). The protein regulates body weight on long-term and appetite on short-term. Preadipocyte differentiation stimulated by ghrelin is found to increase BMI and negatively regulate the anorexigenic effect of leptin. Polymorphism in the GHRL gene is linked to variations in blood pressure, high-density lipoproteins, low-density lipoproteins, serum cholesterol, blood glucose and metabolic syndrome.

其他说明

A sample Certificate of Analysis is available for this product. Please type the word sample in the text box provided for lot number.

象形图

Corrosion

警示用语:

Warning

危险声明

预防措施声明

危险分类

Met. Corr. 1

储存分类代码

8A - Combustible corrosive hazardous materials

闪点(°F)

Not applicable

闪点(°C)

Not applicable

法规信息

新产品

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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访问文档库

Cai-Chun Liu et al.
Scientific reports, 7(1), 14362-14362 (2017-11-01)
Some studies have proved that both acupuncture and moxibustion are very effective for the treatment of CAG. However, little is known about therapeutic mechanism of electro-acupuncture and moxibustion on CAG as well as the difference between them. On the other
T F Lobo et al.
Journal of endocrinological investigation, 42(2), 149-156 (2018-04-27)
The study of adipokines in overweight women with early-onset (diagnosed before 20 weeks) gestational diabetes mellitus (GDM) could help to understand the ethiopathological mechanisms of this disorder. Our aim was to assess adipokine levels in overweight pregnant women with early-onset GDM
Atsushi Kuroda et al.
Geriatrics & gerontology international, 18(6), 886-891 (2018-02-15)
Alzheimer's disease causes loss of appetite, resulting in bodyweight reduction. This, in turn, causes progression of cognitive dysfunction and physical complications that hasten death. Earlier care for loss of appetite is essential in Alzheimer's disease management. Rivastigmine is a therapeutic
A Lindqvist et al.
Molecular and cellular endocrinology, 511, 110835-110835 (2020-05-07)
It is not known how ghrelin affects insulin secretion in human islets from patients with type 2 diabetes (T2D) or whether islet ghrelin expression or circulating ghrelin levels are altered in T2D. Here we sought out to identify the effect
Beate Leppert et al.
Nature communications, 11(1), 561-561 (2020-02-13)
Parabens are preservatives widely used in consumer products including cosmetics and food. Whether low-dose paraben exposure may cause adverse health effects has been discussed controversially in recent years. Here we investigate the effect of prenatal paraben exposure on childhood overweight

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