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种属反应性
human
包装
kit of 96 wells (12 strips x 8 wells)
技术
ELISA: suitable
输入
sample type plasma
sample type cell culture supernatant(s)
sample type serum sample(s)
assay range
inter-assay cv: <12%
intra-assay cv: <10%
sensitivity: 8 pg/ml
检测方法
colorimetric
运输
wet ice
储存温度
−20°C
基因信息
human ... FGF21(26291)
应用
For research use only. Not for use in diagnostic procedures.
Please refer to the attached Protocolfor details.
Please refer to the attached Protocolfor details.
生化/生理作用
Fibroblast growth factor 21 (FGF-21) plays a vital role in the regulation of glucose uptake in mouse 3T3-L1 and primary human adipocytes. In addition, it is also implicated in lipid metabolism and in energy balance. FGF-21 plays a key role in controlling oxidative stress cell response. Overexpression of the gene has been associated with the development of acute pancreatitis, obesity, insulin resistance and metabolic syndrome. Additionally, elevated expression of FGF-21 has been observed in patients with insulin resistance and type 2 diabetes mellitus (T2DM). Thus, it can be considered as a potent target for an effective treatment of diabetes.
其他说明
A sample Certificate of Analysis is available for this product. Please type the word sample in the text box provided for lot number.
警示用语：
Warning
危险声明
预防措施声明
危险分类
Met. Corr. 1
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
法规信息
新产品
Fibroblast growth factor 21 and its novel association with oxidative stress.
Gomez-Samano M A, et al.
Redox Biology, 335-341 null
FGF-21 as a novel metabolic regulator
Kharitonenkov A, et al.
The Journal of Clinical Investigation, 1627-35 null
Circulating FGF-21 Levels in Normal Subjects and in Newly Diagnose Patients with Type 2 Diabetes Mellitus
Chen WW, et al.
Experimental and Clinical Endocrinology & Diabetes, 65-8 null
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