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种属反应性
rat
包装
kit of 96 wells (12 strips x 8 wells)
技术
ELISA: suitable
输入
sample type cell culture supernatant(s)
sample type serum
sample type plasma
assay range
inter-assay cv: <12%
intra-assay cv: <10%
sensitivity: 10 pg/mL
standard curve range: 10.24-2500 pg/mL
检测方法
colorimetric
运输
wet ice
储存温度
−20°C
基因信息
rat ... Mag(29409)
一般描述
The antibody pair provided in this kit recognizes rat MAG / Myelin-associated Glycoprotein / Siglec-4a.
应用
请参考Protocol了解详情。
生化/生理作用
Myelin-associated glycoprotein (MAG) is expressed in Schwann cells and oligodendrocytes. It inhibits the growth of axons. MAG also has a role in signal transduction pathways and cell adhesion. In complex with the neurite outgrowth inhibitor (Nogo) receptor, MAG acts on neurons via the p75 receptor. It activates and modulates the function of Ras homolog gene family, member A (RhoA).
警示用语：
Warning
危险声明
预防措施声明
危险分类
Met. Corr. 1
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
法规信息
新产品
Myelin-associated glycoprotein inhibits microtubule assembly by a Rho-kinase-dependent mechanism.
Mimura F, et al.
The Journal of Biological Chemistry, 281(23), 15970-15979 (2006)
Myelin-associated glycoprotein inhibits the neuronal differentiation of neural progenitors.
Li X, et al.
Neuroreport, 20(7), 708-712 (2009)
Tissue sparing and functional recovery following experimental traumatic brain injury is provided by treatment with an anti-myelin-associated glycoprotein antibody.
Thompson HJ, et al.
The European Journal of Neuroscience, 24(11), 3063-3072 (2006)
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