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关于此项目
NACRES:
NA.32
UNSPSC Code:
41116158
Gene information:
rat ... Mag(29409)
Input:
sample type cell culture supernatant(s)
sample type serum
sample type plasma
sample type serum
sample type plasma
Species reactivity:
rat
Storage temp.:
−20°C
Shipped in:
wet ice
species reactivity
rat
packaging
kit of 96 wells (12 strips x 8 wells)
technique(s)
ELISA: suitable
input
sample type cell culture supernatant(s)
sample type serum
sample type plasma
assay range
inter-assay cv: <12%
intra-assay cv: <10%
sensitivity: 10 pg/mL
standard curve range: 10.24-2500 pg/mL
detection method
colorimetric
shipped in
wet ice
storage temp.
−20°C
Gene Information
rat ... Mag(29409)
Application
请参考Protocol了解详情。
Biochem/physiol Actions
Myelin-associated glycoprotein (MAG) is expressed in Schwann cells and oligodendrocytes. It inhibits the growth of axons. MAG also has a role in signal transduction pathways and cell adhesion. In complex with the neurite outgrowth inhibitor (Nogo) receptor, MAG acts on neurons via the p75 receptor. It activates and modulates the function of Ras homolog gene family, member A (RhoA).
General description
The antibody pair provided in this kit recognizes rat MAG / Myelin-associated Glycoprotein / Siglec-4a.
signalword
Warning
hcodes
pcodes
Hazard Classifications
Met. Corr. 1
存储类别
8A - Combustible corrosive hazardous materials
flash_point_f
Not applicable
flash_point_c
Not applicable
法规信息
新产品
此项目有
Tissue sparing and functional recovery following experimental traumatic brain injury is provided by treatment with an anti-myelin-associated glycoprotein antibody.
Thompson HJ, et al.
The European Journal of Neuroscience, 24(11), 3063-3072 (2006)
Myelin-associated glycoprotein inhibits the neuronal differentiation of neural progenitors.
Li X, et al.
Neuroreport, 20(7), 708-712 (2009)
Myelin-associated glycoprotein inhibits microtubule assembly by a Rho-kinase-dependent mechanism.
Mimura F, et al.
The Journal of Biological Chemistry, 281(23), 15970-15979 (2006)
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