产品名称
Mouse Ins1 / Insulin-1 ELISA Kit, for serum, plasma and cell culture supernatants
species reactivity
mouse
packaging
kit of 96 wells (12 strips x 8 wells)
technique(s)
ELISA: suitable
input
sample type plasma
sample type serum
sample type cell culture supernatant(s)
assay range
inter-assay cv: <12%
intra-assay cv: <10%
sensitivity: 5 μIU/mL
standard curve range: 6.25-400 μIU/ml
detection method
colorimetric
shipped in
wet ice
storage temp.
−20°C
Gene Information
mouse ... Ins1(16333)
Application
小鼠 Ins1/Insulin-1ELISA试剂盒已用于测量化学诱导糖尿病的雄性 Sprague-Dawley 大鼠血清胰岛素的变化。
仅供研究使用。不可用于诊断过程。
请参阅随附的一般ELISA试剂盒 操作步骤 （夹心、竞争性和间接ELISA）
仅供研究使用。不可用于诊断过程。
请参阅随附的一般ELISA试剂盒 操作步骤 （夹心、竞争性和间接ELISA）
Biochem/physiol Actions
某些生物体如小鼠、大鼠和爪蟾具有两个非等位基因型胰岛素基因，即 Ins1 和 Ins2—它们都是官能性的。它们分别在胰腺中编码以 1:2 比例产生的胰岛素。这两个基因在小鼠中是差异表达的。Ins1 基因定位于小鼠 19 号染色体的端粒区。胰腺中合成的胰岛素对维持葡萄糖稳态至关重要。Ins-1 和 Ins-2 基因敲除导致缺乏胰岛素的小鼠出现糖尿病、酮症酸中毒、肝脏脂肪变性和生长迟缓。
General description
本试剂盒中提供的抗体对可识别小鼠胰岛素 1。
Other Notes
本产品提供样本分析证书。
请在批号对应的文本框中输入单词 样本 。
请在批号对应的文本框中输入单词 样本 。
signalword
Warning
hcodes
pcodes
Hazard Classifications
Met. Corr. 1
存储类别
8A - Combustible corrosive hazardous materials
flash_point_f
Not applicable
flash_point_c
Not applicable
法规信息
常规特殊物品
低风险生物材料
此项目有
Phenotypic alterations in insulin-deficient mutant mice.
Duvillie B, et al.
Proceedings of the National Academy of Sciences of the USA, 94(10), 5137-5140 (1997)
Differential expression and imprinting status of Ins1 and Ins2 genes in extraembryonic tissues of laboratory mice.
Deltour L, et al.
Gene expression patterns : GEP, 5(2), 297-300 (2004)
David P Labbé et al.
Nature communications, 10(1), 4358-4358 (2019-09-27)
Systemic metabolic alterations associated with increased consumption of saturated fat and obesity are linked with increased risk of prostate cancer progression and mortality, but the molecular underpinnings of this association are poorly understood. Here, we demonstrate in a murine prostate
Snehal N Chaudhari et al.
Nature chemical biology, 17(1), 20-29 (2020-08-05)
Bariatric surgery, the most effective treatment for obesity and type 2 diabetes, is associated with increased levels of the incretin hormone glucagon-like peptide-1 (GLP-1) and changes in levels of circulating bile acids. The levels of individual bile acids in the
Evaluation of White Sesame Seed Oil on Glucose Control and Biomarkers of Hepatic, Cardiac, and Renal Functions in Male Sprague-Dawley Rats with Chemically Induced Diabetes.
Aslam F, et al.
Journal of Medicinal Food, 20(5), 448-457 (2017)
我们的科学家团队拥有各种研究领域经验，包括生命科学、材料科学、化学合成、色谱、分析及许多其他领域.
联系客户支持