种属反应性
mouse
包装
kit of 96 wells (12 strips x 8 wells)
技术
ELISA: suitable
输入
sample type cell culture supernatant(s)
sample type serum
sample type plasma
assay range
inter-assay cv: <12%
intra-assay cv: <10%
sensitivity: 0.15 ng/mL
standard curve range: 0.205-50 ng/mL
检测方法
colorimetric
运输
wet ice
储存温度
−20°C
基因信息
mouse ... Il18(16173)
一般描述
Interleukin-18 (IL-18) belongs to the IL-1 family of cytokines. It is synthesized as an inactive precursor and converted to the active form by caspase-1. IL-18 is involved in the synthesis of interferon-γ (IFN-γ) and IL-13 from T-cells and natural killer (NK) cells. It is a proinflammatory cytokine that aids in the activation of NK cells and T helper 1 cell response. The antibody pair provided in this kit recognizes mouse interleukin 18.
The antibody pair provided in this kit recognizes Mouse Interleukin 18.
应用
For research use only. Not for use in diagnostic procedures.
Please refer to the attached General ELISA KIT Procedure (sandwich, competitive & Indirect ELISA)
Please refer to the attached General ELISA KIT Procedure (sandwich, competitive & Indirect ELISA)
Mouse Il18 / Interleukin-18 ELISA Kit has been used to detect interleukin-18 in serum samples.
其他说明
A sample Certificate of Analysis is available for this product.
Please type the word sample in the text box provided for lot number.
Please type the word sample in the text box provided for lot number.
试剂盒组分也可单独购买
产品编号
说明
化学品安全说明书
警示用语：
Warning
危险声明
预防措施声明
危险分类
Met. Corr. 1
储存分类代码
8A - Combustible corrosive hazardous materials
闪点(°F)
Not applicable
闪点(°C)
Not applicable
法规信息
常规特殊物品
Charles A Dinarello et al.
Frontiers in immunology, 4, 289-289 (2013-10-12)
Interleukin-18 (IL-18) is a member of the IL-1 family of cytokines. Similar to IL-1β, IL-18 is synthesized as an inactive precursor requiring processing by caspase-1 into an active cytokine but unlike IL-1β, the IL-18 precursor is constitutively present in nearly
T Yoshimoto et al.
Proceedings of the National Academy of Sciences of the United States of America, 96(24), 13962-13966 (1999-11-26)
IL-18 is a proinflammatory cytokine that plays an important role in natural killer cell activation and T helper 1 (Th1) cell responses. Mast cells and basophils are major inducers and effectors of allergic inflammation. Here we show that basophils and
Zufeng Ding et al.
Biochemical and biophysical research communications, 451(4), 637-643 (2014-08-19)
Lectin-like oxidized low-density lipoprotein scavenger receptor-1 (LOX-1) is known to be involved in many pathophysiological events, such as inflammation. To clarify the role of LOX-1 in mtDNA damage and NLRP3 inflammasome activation, we studied wild-type (WT) and LOX-1 knockout (KO)
Jin-Mei Chen et al.
Cytokine, 119, 113-118 (2019-03-25)
Recent studies have provided overwhelming evidence of the involvement of microglia-related molecular networks in the pathogenesis of Alzheimer's diseases (AD). The potential involvement of pro-inflammatory cytokines interleukin (IL)-18, IL-23 and IL-17 on amyloid (Aβ) clearance is still unclear. In this
Benjamin Uzan et al.
EMBO molecular medicine, 6(6), 821-834 (2014-04-30)
Development of novel therapies is critical for T-cell acute leukaemia (T-ALL). Here, we investigated the effect of inhibiting the MAPK/MEK/ERK pathway on T-ALL cell growth. Unexpectedly, MEK inhibitors (MEKi) enhanced growth of 70% of human T-ALL cell samples cultured on
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