推荐产品
种属反应性
mouse
技术
ELISA: suitable
assay range
inter-assay cv: <10%
intra-assay cv: <12%
运输
wet ice
储存温度
−20°C
一般描述
Immunoglobulin M (IgM) is a highly conserved antibody in vertebrates and shows early expression during the immune response. Peritoneal B cells secrete IgM and it exists as a pentamer. IgM plays a key role in engulfing the apoptotic cells. A reduction in the serum IgM levels leads to an increase in autoimmune response and a higher risk for infections. IgM displays polyreactive and autoreactive functionality. It plays a key role in tissue homeostasis by mediating the clearance of tissue-based molecules. The antibody pair provided in this kit recognizes mouse IgM.
应用
请参考Protocol了解详情。
警示用语：
Warning
危险声明
预防措施声明
危险分类
Met. Corr. 1
储存分类代码
8A - Combustible corrosive hazardous materials
闪点(°F)
Not applicable
闪点(°C)
Not applicable
法规信息
新产品
Stefan Malafa et al.
PLoS neglected tropical diseases, 14(2), e0008034-e0008034 (2020-02-06)
Zika virus has recently spread to South- and Central America, causing congenital birth defects and neurological complications. Many people at risk are flavivirus pre-immune due to prior infections with other flaviviruses (e.g. dengue virus) or flavivirus vaccinations. Since pre-existing cross-reactive
A A R Thompson et al.
Science immunology, 2(8) (2017-04-08)
Hypoxia and bacterial infection frequently co-exist, in both acute and chronic clinical settings, and typically result in adverse clinical outcomes. To ameliorate this morbidity, we investigated the interaction between hypoxia and the host response. In the context of acute hypoxia
Lori Broderick et al.
Nature communications, 10(1), 3644-3644 (2019-08-15)
B cell development is a highly regulated process involving multiple differentiation steps, yet many details regarding this pathway remain unknown. Sequencing of patients with B cell-restricted immunodeficiency reveals autosomal dominant mutations in TOP2B. TOP2B encodes a type II topoisomerase, an
Mayte Pérez-Olmeda et al.
Viruses, 12(1) (2020-01-16)
The aim of this study is to evaluate the performance characteristics of the LIAISON XL Zika Capture IgM II. For this purpose we tested 128 samples obtained from recent infections caused by the Zika (ZIKV; 74 samples), dengue (DENV; 10
Petra Emmerich et al.
PLoS neglected tropical diseases, 12(3), e0006366-e0006366 (2018-03-27)
As the most widespread tick-borne arbovirus causing infections in numerous countries in Asia, Africa and Europe, Crimean-Congo Hemorrhagic Fever Virus (CCHFV, family Nairoviridae) was included in the WHO priority list of emerging pathogens needing urgent Research & Development attention. To
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