species reactivity
mouse
technique(s)
ELISA: suitable
assay range
inter-assay cv: <10%
intra-assay cv: <12%
shipped in
wet ice
storage temp.
−20°C
Application
仅供研究使用。不可用于诊断操作。
请参考附带的一般ELISA试剂盒操作程序(夹心、竞争性 & 间接ELISA)
请参考附带的一般ELISA试剂盒操作程序(夹心、竞争性 & 间接ELISA)
Biochem/physiol Actions
免疫球蛋白A(IgA)主要存在于黏膜分泌物中。IgA分IgA1和IgA2两种亚型。IgA在动物中为二聚体,但在人类中呈单体形式。IgA可与IgA受体Fc片段(FCAR)相互作用,激发免疫应答抵御吸入的病原体。由B1淋巴细胞表达的分泌型IgA(S-IgA)可引起吞噬作用和白细胞呼吸爆发。分泌型IgA呈聚合体形式,是第一道免疫防线的关键因子。人乳和初乳中的高水平IgA可为婴儿提供免疫保护。IgA缺乏会导致易感性升高。IgA肾病和IgA骨髓瘤中存在高水平的肾内IgA。乳糜泻病中出现IgA的自身抗体。
General description
该试剂盒中提供的抗体对可识别小鼠IgA。
Other Notes
本产品提供样本检验报告。
请在批号对应的文本框中输入样品 一词。
请在批号对应的文本框中输入样品 一词。
signalword
Warning
hcodes
pcodes
Hazard Classifications
Met. Corr. 1
存储类别
8A - Combustible corrosive hazardous materials
flash_point_f
Not applicable
flash_point_c
Not applicable
法规信息
低风险生物材料
常规特殊物品
此项目有
Shun He et al.
Nature, 566(7742), 115-119 (2019-02-01)
The biochemical response to food intake must be precisely regulated. Because ingested sugars and fats can feed into many anabolic and catabolic pathways1, how our bodies handle nutrients depends on strategically positioned metabolic sensors that link the intrinsic nutritional value
Immunoglobulin A (IgA) deficiency and alternative celiac disease-associated antibodies in sera submitted to a reference laboratory for endomysial IgA testing
Prince HE, et al.
Clinical and Diagnostic Laboratory Immunology, 7(2), 192-196 (2000)
Anna-Carin Lundell et al.
Scientific reports, 7(1), 15503-15503 (2017-11-16)
Boys present with higher proportions of immature/naïve CD5
Chise Suzuki et al.
PloS one, 12(12), e0188985-e0188985 (2017-12-09)
The molecular mechanisms of strain-specific probiotic effects and the impact of the oral administration of probiotic strains on the host's gene expression are not yet well understood. The aim of this study was to investigate the strain-specific effects of probiotic
Function of immunoglobulin A in immunity
Kerr, MA
Gut, 47(6), 751-752 (2000)
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