种属反应性
human
包装
kit of 96 wells (12 strips x 8 wells)
技术
ELISA: suitable
输入
sample type cell culture supernatant(s)
sample type serum
sample type plasma
assay range
inter-assay cv: <12%
intra-assay cv: <10%
sensitivity: 15 pg/mL
standard curve range: 16.38-4000 pg/mL
检测方法
colorimetric
运输
wet ice
储存温度
−20°C
基因信息
human ... PLAUR(5329)
一般描述
The antibody pair provided in this kit recognizes human Urokinase Plasminogen Activator Surface Receptor.
应用
请参考Protocol了解详情。
生化/生理作用
Plasminogen activator, urokinase receptor (PLAUR) is implicated in tumor invasion, angiogenesis and metastasis. It acts as a key regulator of cell-surface plasminogen activator. It is involved in various normal and pathological processes. Overexpression of the gene has been observed in various types of cancers, including head and neck squamous cell carcinoma (HNSCC). Thus, it is considered as an potent biomarker for targeted imaging or therapy. Elevated expression of PLAUR leads to the progression of kidney disease in children.
其他说明
A sample Certificate of Analysis is available for this product.
Please type the word sample in the text box provided for lot number.
Please type the word sample in the text box provided for lot number.
警示用语：
Warning
危险声明
预防措施声明
危险分类
Met. Corr. 1
储存分类代码
8A - Combustible corrosive hazardous materials
闪点(°F)
Not applicable
闪点(°C)
Not applicable
法规信息
新产品
Fei Huang et al.
Mediators of inflammation, 2020, 7850179-7850179 (2020-04-24)
The soluble urokinase plasminogen activator receptor (suPAR) is associated with kidney diseases and is used as a prognostic factor of renal function progression. The aim of this study was to explore whether circulating suPAR was associated with antineutrophil cytoplasmic autoantibody-
Ümmügülsüm Can et al.
Journal of investigative medicine : the official publication of the American Federation for Clinical Research, 62(7), 938-943 (2014-08-16)
Chronic obstructive pulmonary disease (COPD) results from an abnormal inflammatory response of the lungs to noxious particles or gases. Serum soluble urokinase-type plasminogen activator receptor (suPAR) is a glycoprotein secreted during infections and inflammation. The main goal of this study
Assignment of the Urokinase-Type Plasminogen Activator Receptor Gene (PLAUR) to Chromosome 1 9q 13.1 -q 13.2
B?rglum A D, et al.
American Journal of Human Genetics, 50(3), 492-492 (1992)
Association of Serum Soluble Urokinase Receptor Levels With Progression of Kidney Disease in Children.
Schaefer F, et al.
JAMA Pediatrics, 171(11), e172914-e172914 (2017)
uPAR-targeted optical near-infrared (NIR) fluorescence imaging and PET for image-guided surgery in head and neck cancer: proof-of-concept in orthotopic xenograft model
Christensen A, et al.
Oncotarget, 8(9), 15407-15407 (2017)
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