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种属反应性
human
包装
kit of 96 wells (12 strips x 8 wells)
技术
ELISA: suitable
assay range
inter-assay cv: <10%
intra-assay cv: <12%
检测方法
colorimetric
运输
wet ice
储存温度
−20°C
基因信息
human ... SSSCA1(10534)
一般描述
The SSSCA1 (Sjoegren syndrome/scleroderma autoantigen 1) gene codes for a cell cycle inhibitor, also called as p27. The SSSCA1 gene is mapped to human chromosome 11q13.1.
The antibody pair provided in this kit recognizes human SSSCA1.
应用
请参考Protocol了解详情。
生化/生理作用
Sjoegren Syndrome Autoantigen 1 is an important cyclin-dependent kinase complexes inhibitor and prevents the G1 to S phase transition during cell cycle. It is regulated by ubiquitin-proteasome. The Sjoegren Syndrome Autoantigen 1 gene expression is downregulated in cancer and indicates poor prognosis.
警示用语：
Warning
危险声明
预防措施声明
危险分类
Met. Corr. 1
储存分类代码
8A - Combustible corrosive hazardous materials
闪点(°F)
Not applicable
闪点(°C)
Not applicable
法规信息
新产品
Loss of 3p26. 3 is an independent prognostic factor in patients with oral squamous cell carcinoma.
Uchida K, et al.
Oncology Reports, 26(2), 463-469 (2011)
Subcellular localization of p27 and prostate cancer recurrence: automated digital microscopy analysis of tissue microarrays.
Ananthanarayanan V, et al.
Human Pathology, 42(6), 873-881 (2011)
Expression of CRM1 in human gliomas and its significance in p27 expression and clinical prognosis.
Shen A, et al.
Neurosurgery, 65(1), 153-160 (2009)
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