species reactivity
human
packaging
kit of 96 wells (12 strips x 8 wells)
technique(s)
ELISA: suitable
input
sample type plasma
sample type serum
sample type cell culture supernatant(s)
assay range
inter-assay cv: <12%
intra-assay cv: <10%
sensitivity: 2.5 pg/mL
standard curve range: 2.03-130 pg/mL
detection method
colorimetric
shipped in
wet ice
storage temp.
−20°C
Gene Information
human ... GCG(2641)
Application
请参考Protocol了解详情。
Biochem/physiol Actions
Glucagon-like peptide-1 (GLP-1) treatment helps to lower the risk of stroke in diabetic patients and to be neuroprotective in experimental stroke models. It participates in glucose homeostasis and has an impact on the cardiovascular system. GLP-1 may promote pancreatic β-cell proliferation and neogenesis. It enhances insulin release after a meal and triggers insulin transcription and biosynthesis.
General description
Glucagon-like peptide-1 (GLP-1), a peptide hormone is liberated from endocrine epithelial cells of the small intestine. The proglucagon gene (GCG) codes for glucagon, glucagon-like peptide-1 (GLP-1), and glucagon-like peptide-2 (GLP-2).
Other Notes
A sample Certificate of Analysis is available for this product.
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signalword
Warning
hcodes
pcodes
Hazard Classifications
Met. Corr. 1
存储类别
8A - Combustible corrosive hazardous materials
flash_point_f
Not applicable
flash_point_c
Not applicable
法规信息
新产品
此项目有
David R Powell et al.
The Journal of pharmacology and experimental therapeutics, 350(2), 232-242 (2014-05-23)
Treatments that lower blood glucose levels and body weight should benefit patients with type 2 diabetes mellitus (T2DM). We developed LX4211 [(2S,3R,4R,5S,6R)-2-(4-chloro-3-(4-ethoxybenzyl)phenyl)-6-(methylthio)tetrahydro-2H-pyran-3,4,5-triol], an orally available small molecule that decreases postprandial glucose excursions by inhibiting intestinal sodium/glucose cotransporter 1 (SGLT1) and
Cristina Barale et al.
Thrombosis research, 180, 74-85 (2019-06-24)
The incretin hormone Glucagon-like peptide 1(GLP-1) plays a pivotal role in maintaining glucose homeostasis with effects also on the cardiovascular system. GLP-1 influences platelet functions by increasing the inhibitory action of nitric oxide (NO) and reducing oxidative stress. To date
Martin Larsson et al.
Cardiovascular diabetology, 18(1), 91-91 (2019-07-17)
Glucagon-like peptide-1 (GLP-1) treatment has been shown to reduce stroke incidence in diabetes and also to be neuroprotective in experimental stroke models. The prognostic value of endogenous levels of GLP-1 in the recovery phase after stroke remains to be elucidated. The
Charles-Étienne Plourde et al.
Obesity (Silver Spring, Md.), 22(8), 1838-1846 (2014-04-25)
To assess the rapid improvement of insulin sensitivity and β-cell function following biliopancreatic diversion with duodenal switch (BPD-DS) and determine the role played by caloric restriction in these changes. Standard meals were administrated before and on day 3, 4, and
Tianru Jin
The Journal of endocrinology, 198(1), 17-28 (2008-06-26)
The proglucagon gene (gcg) encodes a number of peptide hormones that are of cell-type specifically expressed in the pancreatic islets, the distal ileum and the large intestine, as well as certain brain neuronal cells. These hormones are important in controlling
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