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安全信息

RAB0618

Sigma-Aldrich

人APOC3 /载脂蛋白C-III ELISA试剂盒

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UNSPSC代码:
41116158
NACRES:
NA.32

种属反应性

human

包装

kit of 96 wells (12 strips x 8 wells)

技术

ELISA: suitable

输入

sample type plasma
sample type cell culture supernatant(s)
sample type serum

assay range

inter-assay cv: <12%
intra-assay cv: <10%
sensitivity: 2.5 pg/mL
standard curve range: 2.44-10000 pg/mL

检测方法

colorimetric

运输

wet ice

储存温度

−20°C

基因信息

human ... APOC3(345)

一般描述

The antibody pair provided in this kit recognizes Human Apolipoprotein C3.
ApoC-III is a glycoprotein that has 79 amino acids. It is coded by APOC3 gene. APOC3 is expressed in the liver and intestine. This gene is located on human chromosome 11.

应用

请参考Protocol了解详情。

生化/生理作用

Apolipoprotein C-III (APOC3) has the ability to prevent lipoprotein lipase (LPL) and hepatic lipase activity. It is considered as a major modulator of triglyceride metabolism.

其他说明

A sample Certificate of Analysis is available for this product.
Please type the word sample in the text box provided for lot number.

试剂盒组分也可单独购买

产品编号
说明
化学品安全说明书

  • RABTMB3ELISA Colorimetric TMB Reagent (HRP Substrate, Item H)化学品安全说明书

  • RABSTOP3ELISA Stop Solution (Item I)化学品安全说明书

  • RABWASH420X Wash Buffer (Item B)化学品安全说明书

象形图

Corrosion

警示用语:

Warning

危险声明

预防措施声明

危险分类

Met. Corr. 1

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

法规信息

常规特殊物品

分析证书(COA)

输入产品批号来搜索 分析证书(COA) 。批号可以在产品标签上"批“ (Lot或Batch)字后找到。

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Åsa Sandin et al.
Scandinavian journal of clinical and laboratory investigation, 80(3), 230-235 (2020-02-29)
Apolipoprotein CIII (apoCIII) is associated with triglyceride (TG)-rich particles like VLDL and exerts an inhibitory effect of lipoprotein lipase. Increased levels are related to cardiovascular diseases and diabetes and therefore apoCIII has been proposed as a useful biomarker. Even if
Keishi Hata et al.
Biomedical research (Tokyo, Japan), 41(1), 33-42 (2020-02-25)
We investigated lipid metabolism in PXB-cells, which are human primary hepatocytes isolated from liver-humanized mice, and HepG2 and HuH-7 human hepatoma cell lines. Lipoprotein levels were higher in PXB-cells than in the 2 other cell lines, and PXB-cells mainly released
Targeting APOC3 in the familial chylomicronemia syndrome.
Gaudet D, et al.
The New England Journal of Medicine, 371(23), 2200-2206 (2014)
Apolipoprotein CIII Levels and Incident Coronary Artery Disease Risk: The EPIC-Norfolk Prospective Population Study.
van Capelleveen JC, et al.
Arteriosclerosis, Thrombosis, and Vascular Biology, 37(6), 1206-1212 (2017)
Li Li et al.
International journal of molecular medicine, 45(5), 1409-1416 (2020-04-24)
The aim of the present study was to identify potential serum biomarkers for insulin resistance (IR) in patients with polycystic ovary syndrome (PCOS) by comparing the differences in serum protein expression levels between PCOS patients with and without IR. PCOS

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