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种属反应性
human
包装
kit of 96 wells (12 strips x 8 wells)
技术
ELISA: suitable
capture ELISA: suitable
输入
sample type serum
sample type cell culture supernatant(s)
sample type plasma
sample type urine
assay range
inter-assay cv: <12%
intra-assay cv: <10%
sensitivity: 1 pg/mL
standard curve range: 0.55-400 pg/mL
检测方法
colorimetric
运输
wet ice
储存温度
−20°C
基因信息
human ... TNFRSF1A(7132)
一般描述
The Human sTNF RI (soluble tumor necrosis factor receptor I) ELISA (Enzyme-Linked Immunosorbent Assay) kit is an in vitro enzyme- linked immunosorbent assay for the quantitative measurement of human sTNF RI in serum, plasma, cell culture supernatants and urine.
免疫原
Recombinant Human TNF RI
应用
请参考Protocol了解详情。
生化/生理作用
Tumour necrosis factor (TNF) receptor superfamily member 1A is a type I single transmembrane glycoprotein. Signal transduction mediated by binding of TNFα regulates inflammatory, immune responses and apoptotic pathway. TNF receptor 1 is implicated in the end-stage renal disease and associated mortality. Mutations in TNF receptor 1 causes autosomal dominant tumor necrosis factor receptor-associated periodic syndrome (TRAPS). Polymorphism in TNF receptor 1 causes multiple sclerosis.
其他说明
A sample Certificate of Analysis is available for this product.
Please type the word sample in the text box provided for lot number.
Please type the word sample in the text box provided for lot number.
试剂盒组分也可单独购买
产品编号
说明
化学品安全说明书
A novel TNFRSF1A gene mutation in a patient with tumor necrosis factor receptor-associated periodic syndrome
Khabazi A, et al.
Hematology/oncology and Stem Cell Therapy, 11(3), 175-177 (2018)
TNF receptor 1 genetic risk mirrors outcome of anti-TNF therapy in multiple sclerosis
Gregory AP, et al.
Nature, 488(7412), 508-511 (2012)
Circulating TNF receptors 1 and 2 predict mortality in patients with end-stage renal disease undergoing dialysis
Gohda T, et al.
Scientific Reports, 7, 43520-43520 (2017)
Kazuo Kubota et al.
Journal of clinical immunology, 34(5), 584-593 (2014-04-25)
To investigate clinical presentation, genetic background and cytokine profile of Japanese sporadic cases of periodic fever, aphthous stomatitis, pharyngitis and adenitis (PFAPA) syndrome. Nine PFAPA syndrome patients were recruited. DNA sequence analysis of auto inflammatory disorder susceptibility genes, MEFV, MVK
Anil K Taneja et al.
International journal of cardiology, 175(2), 253-260 (2014-06-01)
Heart failure activates neurohormones, and elevated levels of brain natriuretic peptide (BNP) are associated with adverse outcomes. The SENIORS trial showed that nebivolol, a highly selective beta-1 antagonist with vasodilating properties, reduced the composite outcome of all cause mortality or
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