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Merck
CN

RAB0460

人TGF-β 1 ELISA试剂盒

for serum, plasma, and cell culture supernatants

别名:

TGF-beta-1, Transforming growth factor beta-1

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关于此项目

NACRES:
NA.32
UNSPSC Code:
41116158
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产品名称

人TGF-β 1 ELISA试剂盒, for serum, plasma, and cell culture supernatants

species reactivity

human

packaging

kit of 96 wells (12 strips x 8 wells)

technique(s)

ELISA: suitable
capture ELISA: suitable

input

sample type serum
sample type cell culture supernatant(s)
sample type plasma

assay range

inter-assay cv: <12%
intra-assay cv: <10%
sensitivity: 80 pg/mL
standard curve range: 0.0823-60 ng/mL

detection method

colorimetric

shipped in

wet ice

storage temp.

−20°C

Gene Information

human ... TGFB1(7040)

Application

仅供研究使用。不可用于诊断操作。
人转化生长因子-β1(TGF-β1)ELISA试剂盒已被用于测量肾小管细胞释放的TGF-β1水平。

Biochem/physiol Actions

转化生长因子-1β1(TGF-β1)是一种多能细胞因子,在外周CD4+CD25+ 调节性T细胞的体内平衡和体内FOXP3(叉头框P3)表达的调节中具有重要作用。TGF-β1与其受体结合,可激活参与基因调节的SMAD蛋白家族成员。研究表明,循环转化生长因子-β1(TGF-β1)的表达降低可能有助于系统性红斑狼疮(SLE)的发展。 TGF-β1的多态性与类风湿性关节炎(RA)和尘肺病的发病有关。 系统性硬化症(SSc)患者的血清TGF-β1表达升高。 血清TGF-β1是格林-巴利综合征(GBS)和SSc的潜在生物标志物。

General description

人TGF-β 1 ELISA(酶联免疫吸附测定)试剂盒采用体外酶联免疫吸附测定法,定量测定人血清、血浆、细胞培养物上清液中的TGF-β 1含量。

Immunogen

重组人 TGF-β 1

Other Notes

本产品提供样本分析证书。
请在批号对应的文本框中输入单词 sample

pictograms

Corrosion

signalword

Warning

hcodes

Hazard Classifications

Met. Corr. 1

存储类别

8A - Combustible corrosive hazardous materials

法规信息

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历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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访问文档库

XueXuan Zhang et al.
International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases, 59, 110-117 (2017-04-19)
To investigate PI3K-Akt-mTOR signaling pathway changes and the proliferation of FoxP3+Treg cells in patients with active tuberculosis. We isolated PBMCs and CD4+CD25+FoxP3+Treg cells from peripheral blood collected from patients with active tuberculosis and healthy controls. We compared the proportion and
Increased serum concentrations of transforming growth factor-?1 (TGF-?1) in patients with Guillain-Barre syndrome.
Chang KH
Clinica Chimica Acta; International Journal of Clinical Chemistry, 461, 8-13 (2016)
Reassessing the Role of the Active TGF-?1 as a Biomarker in Systemic Sclerosis: Association of Serum Levels with Clinical Manifestations.
Dantas AT
Disease Markers (2016)
Association between circulating transforming growth factor-?1 level and polymorphisms in systemic lupus erythematosus and rheumatoid arthritis: A meta-analysis.
Lee YH and Bae SC
Cellular and molecular biology (Noisy-le-Grand, France), 63(1), 53-59 (2017)
Qiao Huang et al.
Experimental and therapeutic medicine, 18(1), 692-698 (2019-07-02)
NEF is a tumor suppressing long non-coding (lnc)RNA in hepatocellular carcinoma. Based on current literature, the involvement of NEF in other human diseases is still unknown. The current study aimed to investigate the potential involvement of NEF in glioma, which

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