RAB0430
人类 ShhN ELISA 试剂盒
for serum, plasma, cell culture supernatants and urine
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关于此项目
NACRES:
NA.32
UNSPSC Code:
41116158
Gene information:
human ... SHH(6469)
Input:
sample type cell culture supernatant(s)
sample type serum
sample type urine
sample type plasma
sample type serum
sample type urine
sample type plasma
Species reactivity:
human
Storage temp.:
−20°C
Shipped in:
wet ice
产品名称
人类 ShhN ELISA 试剂盒, for serum, plasma, cell culture supernatants and urine
species reactivity
human
packaging
kit of 96 wells (12 strips x 8 wells)
technique(s)
ELISA: suitable
capture ELISA: suitable
input
sample type cell culture supernatant(s)
sample type serum
sample type urine
sample type plasma
assay range
inter-assay cv: <12%
intra-assay cv: <10%
sensitivity: 42 pg/mL
standard curve range: 40.96-10000 pg/mL
(Assay Diluent C)
inter-assay cv: <12%
intra-assay cv: <10%
sensitivity: 8 pg/mL
standard curve range: 40.96-10000 pg/mL
(Assay Diluent B)
detection method
colorimetric
shipped in
wet ice
storage temp.
−20°C
Gene Information
human ... SHH(6469)
Application
请参考Protocol了解详情。
Biochem/physiol Actions
Sonic hedgehog (Shh) is a secreted glycoprotein involved in embryonic morphogenic development of several tissues. It has a role in fracture healing and regeneration. In the canonical pathway, the protein associates with its receptor patched (Ptc-1), de-represses smoothened (Smo) and activates the Gli family of transcription factors. Mutations in the Shh pathway have been linked to developmental diseases and cancer. Shh plays a vital role in axon growth and guidance throughout the brain development. Shh stimulates neurite outgrowth by overcoming neurite growth inhibitory environment associated with glial scar.
General description
The Human Shh-N (Sonic Hedgehog N Terminus) ELISA (Enzyme-Linked Immunosorbent Assay) kit is an in vitro enzyme- linked immunosorbent assay for the quantitative measurement of human Shh-N in serum, plasma, cell culture supernatants and urine.
Immunogen
Recombinant Human ShhN
Other Notes
A sample Certificate of Analysis is available for this product.
Please type the word sample in the text box provided for lot number.
Please type the word sample in the text box provided for lot number.
Hazard Classifications
Met. Corr. 1
signalword
Warning
hcodes
pcodes
存储类别
8A - Combustible corrosive hazardous materials
法规信息
新产品
此项目有
Sonic hedgehog stimulates neurite outgrowth in a mechanical stretch model of reactive-astrogliosis.
Berretta A
Scientific Reports, 6, 21896-21896 (2016)
Expression and Role of Sonic Hedgehog in the Process of Fracture Healing with Aging.
Matsumoto K
In Vivo, 30(2), 99-105 (2016)
Xuqi Li et al.
Clinical cancer research : an official journal of the American Association for Cancer Research, 20(16), 4326-4338 (2014-06-21)
Pancreatic cancer is characterized by stromal desmoplasia and perineural invasion (PNI). We sought to explore the contribution of pancreatic stellate cells (PSC) activated by paracrine Sonic Hedgehog (SHH) in pancreatic cancer PNI and progression. In this study, the expression dynamics
Xuanming Shi et al.
Nature communications, 5, 5425-5425 (2014-11-06)
The Sonic hedgehog (Shh) signalling pathway plays important roles during development and in cancer. Here we report a Shh-induced epigenetic switch that cooperates with Gli to control transcription outcomes. Before induction, poised Shh target genes are marked by a bivalent
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