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种属反应性
human
包装
kit of 96 wells (12 strips x 8 wells)
技术
ELISA: suitable
capture ELISA: suitable
输入
sample type plasma
sample type cell culture supernatant(s)
sample type urine
sample type serum
assay range
inter-assay cv: <12%
intra-assay cv: <10%
sensitivity: 20 pg/mL
standard curve range: 0.041-30 ng/mL
检测方法
colorimetric
运输
wet ice
储存温度
−20°C
基因信息
human ... SELP(6403)
一般描述
The Human P-Selectin ELISA (Enzyme-Linked Immunosorbent Assay) kit is an in vitro enzyme-linked immunosorbent assay for the quantitative measurement of human P-Selectin in serum, plasma, cell culture supernatants and urine.P-selectin, also known as cluster of differentiation 62 (CD62) or granule membrane protein 140 (GMP-140), is a Ca2+-dependent lectin. It is expressed within alpha-granules of platelets and the Weibel-Palade bodies of endothelial cells.
免疫原
Recombinant Human P-Selectin
应用
Please refer to the attached General ELISA KIT Procedure (sandwich, competitive & Indirect ELISA)
Human P-Selectin ELISA (Enzyme-Linked Immunosorbent Assay) kit has been used in ELISA to quantify P-selectin levels in platelet lysates.
For research use only. Not for use in diagnostic procedures.
Human P-Selectin ELISA (Enzyme-Linked Immunosorbent Assay) kit has been used in ELISA to quantify P-selectin levels in platelet lysates.
For research use only. Not for use in diagnostic procedures.
生化/生理作用
P-selectin serves as an adhesion molecule and plays an important role in leukocyte rolling and attachment. In addition, it also acts a receptor for myeloid cells by associating with sialylated, fucosylated lactosaminoglycans. Overexpression of P-selectin has been observed in apparently healthy women at risk for future vascular events.
其他说明
A sample Certificate of Analysis is available for this product.
Please type the word sample in the text box provided for lot number.
Please type the word sample in the text box provided for lot number.
试剂盒组分也可单独购买
产品编号
说明
化学品安全说明书
警示用语：
Warning
危险声明
预防措施声明
危险分类
Met. Corr. 1
储存分类代码
8A - Combustible corrosive hazardous materials
法规信息
新产品
Effects of selenium in the MAPK signaling cascade.
Rashtchizadeh N, et al.
Journal of cardiovascular and thoracic research, 7(3), 107-107 (2015)
Identification of a specific glycoprotein ligand for P-selectin (CD62) on myeloid cells.
Moore K L, et al.
The Journal of Cell Biology, 118(2), 445-456 (1992)
Soluble P-selectin and the risk of future cardiovascular events.
Ridker P M, et al.
Circulation, 103(4), 491-495 (2001)
Nadereh Rashtchizadeh et al.
Journal of cardiovascular and thoracic research, 7(3), 107-112 (2015-10-03)
This study aimed to discover by which mechanism selenium (Se) suppresses stimulated platelets stimulation in oxidative stress underlying diseases. Human platelets pretreated with Se and stimulated by Cu(2+)-oxidized low density of lipoprotein (OxLDL) or thrombin before assessment of P-selectin and
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