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种属反应性
human, mouse, rat
包装
kit of 96 wells (12 strips x 8 wells)
技术
ELISA: suitable
enzyme immunoassay: suitable
输入
sample type serum
sample type culture supernatant(s)
sample type plasma
sample type cell lysate
assay range
inter-assay cv: <15%
intra-assay cv: <10%
sensitivity: 1.66 pg/mL
standard curve range: 0.1–1000 pg/mL
检测方法
colorimetric
运输
wet ice
储存温度
−20°C
基因信息
human ... NPPB(4879)
一般描述
BNP 酶免疫分析 (EIA) 试剂盒是基于竞争酶免疫分析原理的体外定量检测 BNP 肽的方法。
免疫原
脑钠肽，合成肽
应用
仅用于研究目的。不用于诊断程序。
脑钠肽 EIA 试剂盒已用于测定人新生儿心室心肌细胞培养分泌的脑钠肽 (BNP)。
脑钠肽 EIA 试剂盒已用于测定人新生儿心室心肌细胞培养分泌的脑钠肽 (BNP)。
生化/生理作用
哺乳动物脑利钠肽 (BNP) 和心房利钠肽 (ANP) 具有调节血压和心脏重构等多种生理功能。BNP 可作为有症状的左心室 (LV) 功能障碍患者左心室舒张末压升高的潜在生物标志物。在急性心肌梗死 (AMI) 患者中观察到 BNP 表达升高。BNP 还涉及多种生物学功能，如利尿、利钠、降压和抑制醛固酮分泌。
警示用语：
Warning
危险声明
预防措施声明
危险分类
Met. Corr. 1
储存分类代码
8A - Combustible corrosive hazardous materials
闪点(°F)
Not applicable
闪点(°C)
Not applicable
法规信息
常规特殊物品
Cara Tomas et al.
Open heart, 4(2), e000697-e000697 (2018-01-19)
To explore levels of the brain natriuretic peptide (BNP) and how these associate with the cardiac abnormalities recently identified in chronic fatigue syndrome (CFS). Cardiac magnetic resonance examinations were performed using 3T Philips Intera Achieva scanner (Best, Netherlands) in CFS
Csaba Matyas et al.
Hepatology (Baltimore, Md.), 71(4), 1391-1407 (2019-08-31)
Hepatic cardiomyopathy, a special type of heart failure, develops in up to 50% of patients with cirrhosis and is a major determinant of survival. However, there is no reliable model of hepatic cardiomyopathy in mice. We aimed to characterize the
Héctor Fernández-Susavila et al.
Journal of the American Heart Association, 6(12) (2017-12-06)
Besides the relevant role of brain-type natriuretic peptide (BNP) as biomarker of cardioembolic strokes, new experimental evidences suggest that this peptide may mediate neuroprotective effects. In this study, we have evaluated for the first time the clinical association between BNP
Plasma brain natriuretic peptide as a biochemical marker of high left ventricular end-diastolic pressure in patients with symptomatic left ventricular dysfunction.
Maeda K
American Heart Journal, 135(5 pt 1), 825-832 (1998)
Azar Hosseini et al.
Frontiers in pharmacology, 13, 909079-909079 (2022-06-28)
Background: Doxorubicin as an anti-cancer drug causes cardiotoxicity, limiting its tolerability and use. The mechanism of toxicity is due to free radical production and cardiomyocytes injury. This research evaluated Rheum turkestanicum (R.turkestanicum) extract against doxorubicin cardiotoxicity due to its considerable
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