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种属反应性
mouse
包装
kit of 96 wells (12 strips x 8 wells)
技术
ELISA: suitable
capture ELISA: suitable
输入
sample type serum
sample type plasma
sample type cell culture supernatant(s)
assay range
inter-assay cv: <12%
intra-assay cv: <10%
sensitivity: 5 pg/mL
standard curve range: 2.74-2000 pg/mL
检测方法
colorimetric
运输
wet ice
储存温度
−20°C
基因信息
mouse ... Kitl(17311)
一般描述
The Mouse SCF ELISA (Enzyme-Linked Immunosorbent Assay) kit is an in vitro enzyme-linked immunosorbent assay for the quantitative measurement of mouse SCF in serum, plasma, cell culture supernatants and urine.
免疫原
Recombinant Mouse SCF
应用
请参考Protocol了解详情。
生化/生理作用
Stem cell Factor (SCF) or kit ligand or steel factor or mast cell growth factor is a growth factor essential to bring about various homeostatic events like maintenance of hematopoietic stem cells, mast cells and melanocytes. SCF is essential for maintaining mature melanocytes and to promote hair pigmentation. In ovary, granulosa cells produce kit ligand, which promotes activation and growth of primordial follicles. Kit ligand converts primordial follicles to primary follicles and leads to subsequent follicle growth. Kit ligand acts as an anti-apoptotic factor and causes the growth of primordial follicles in mouse fetal ovary. Kit signalling is crucial for growth of interstitial cells of Cajal (ICCs) and regulates gastrointestinal motility in fetal mice.
其他说明
A sample Certificate of Analysis is available for this product.
Please type the word sample in the text box provided for lot number.
Please type the word sample in the text box provided for lot number.
试剂盒组分也可单独购买
产品编号
说明
化学品安全说明书
Identification of hair shaft progenitors that create a niche for hair pigmentation
Liao CP, et al.
Genes & Development, 31, 1-13 (2017)
Stem cell factor/Kit signal insufficiency contributes to hypoxia-induced intestinal motility dysfunctions in neonatal mice
Ren H, et al.
Digestive Diseases and Sciences, 62(5), 1193-1203 (2017)
Charlotte B Westbury et al.
Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology, 111(2), 206-211 (2014-04-22)
Mast cells are involved in the pathogenesis of radiation fibrosis and may be a therapeutic target. The mechanism of increased mast cell number in relation to acute and late tissue responses in human skin was investigated. Punch biopsies of skin
Lawrence M Knab et al.
Molecular cancer research : MCR, 12(10), 1440-1448 (2014-06-20)
Pancreatic ductal adenocarcinoma (PDAC) is associated with a pronounced fibro-inflammatory stromal reaction that contributes to tumor progression. A critical step in invasion and metastasis is the epithelial-to-mesenchymal transition (EMT), which can be regulated by the Snail family of transcription factors.
Armelle Calipel et al.
Clinical & experimental metastasis, 31(5), 553-564 (2014-03-22)
Imatinib mesylate is used in targeted therapy of cancer to inhibit type III tyrosine kinase receptors, such as KIT and platelet-derived growth factor receptors (PDGFRs). Expression of KIT in uveal melanoma (UM) suggests that this receptor may be the target
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