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种属反应性
human
包装
kit of 96 wells (12 strips x 8 wells)
技术
ELISA: suitable
capture ELISA: suitable
输入
sample type plasma
sample type serum
sample type conditioned medium
sample type urine
assay range
inter-assay cv: <12%
intra-assay cv: <10%
sensitivity: 50 pg/mL
standard curve range: 0.05-40 ng/mL
检测方法
colorimetric
运输
wet ice
储存温度
−20°C
基因信息
human ... IGHG1(3500)
一般描述
The Human IgG1 ELISA (Enzyme-Linked Immunosorbent Assay) kit is an in vitro enzyme-linked immunosorbent assay for the quantitative measurement of human IgG1 in serum and plasma.
免疫原
Recombinant Human IGG1
应用
请参考Protocol了解详情。
生化/生理作用
Immunoglobulin heavy constant gamma 1 (IGHG1), or IgG1, expressed in pancreatic cancer cells might be implicated in tumor cell proliferation and immune evasion mechanisms. siRNA targeted silencing of IGHG1 retards cell growth and induces apoptosis in human prostate cancer cell.
其他说明
A sample Certificate of Analysis is available for this product.
Please type the word sample in the text box provided for lot number.
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Roxanne Collin et al.
Journal of immunology (Baltimore, Md. : 1950), 193(7), 3503-3512 (2014-08-29)
Autoimmune diseases result from a break in immune tolerance. Various mechanisms of peripheral tolerance can protect against autoimmunity, including immunoregulatory CD4(-)CD8(-) double-negative (DN) T cells. Indeed, we have previously shown that diabetes-prone mouse strains exhibit a low proportion of DN
Bin Pan et al.
Molecular biology reports, 40(1), 27-33 (2012-11-03)
To investigate the immunoglobulin G (IgG) expression in prostate cancer cell lines and explore the effects of IGHG1 gene knockdown on PC3 cell growth and apoptosis. Flow cytometry, qPCR and western blot were used to demonstrate IgG expression in prostate
Xiaoyan Li et al.
Pancreas, 40(5), 753-761 (2011-06-10)
To investigate the expression of Igγ-1 chain C region (IGHG1) in human pancreatic carcinomas and determine the biological function of IGHG1 expression in immune evasion mechanisms. Comparative proteomic analysis was used to detect the differential expression of IGHG1 in human
Joseph R Brady et al.
Biotechnology and bioengineering, 117(2), 543-555 (2019-10-28)
Komagataella phaffii, also known as Pichia pastoris, is a common host for the production of biologics and enzymes, due to fast growth, high productivity, and advancements in host engineering. Several K. phaffii variants are commonly used as interchangeable base strains
Arjan van der Flier et al.
PloS one, 10(4), e0124930-e0124930 (2015-04-24)
We recently developed a longer lasting recombinant factor VIII-Fc fusion protein, rFVIIIFc, to extend the half-life of replacement FVIII for the treatment of people with hemophilia A. In order to elucidate the biological mechanism for the elongated half-life of rFVIIIFc
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