RAB0100
人粒巨噬细胞集落刺激因子/ CSF2 ELISA试剂盒
for serum, plasma, cell culture supernatant and urine
别名:
GM-CSF
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关于此项目
NACRES:
NA.32
UNSPSC Code:
41116158
Gene information:
human ... CSF2(1437)
Input:
sample type serum
sample type urine
sample type plasma
sample type cell culture supernatant(s)
sample type urine
sample type plasma
sample type cell culture supernatant(s)
Species reactivity:
human
Storage temp.:
−20°C
Shipped in:
wet ice
产品名称
人粒巨噬细胞集落刺激因子/ CSF2 ELISA试剂盒, for serum, plasma, cell culture supernatant and urine
species reactivity
human
packaging
kit of 96 wells (12 strips x 8 wells)
technique(s)
ELISA: suitable
capture ELISA: suitable
input
sample type serum
sample type urine
sample type plasma
sample type cell culture supernatant(s)
assay range
inter-assay cv: <12%
intra-assay cv: <10%
sensitivity: 2 pg/mL
standard curve range: 2.05-500 pg/mL
detection method
colorimetric
shipped in
wet ice
storage temp.
−20°C
Gene Information
human ... CSF2(1437)
Application
请参考Protocol了解详情。
Biochem/physiol Actions
GM-CSF (granulocyte-macrophage colony-stimulating factor, also referred to as CSF2) is a hematopoietic growth factor that stimulates the development of neutrophils and macrophages and promotes the proliferation and development of early erythroid megakaryocytic and eosinophilic progenitor cells. It enhances neutrophil migration. GM-CSF plays a crucial role in inflammatory and autoimmune diseases. In neutrophils, it promotes the expression of TLR2 (toll-like receptor) and TLR2-associated interleukin 8 responses, thereby eliminating microbial attack.
General description
The Human GM-CSF ELISA (Enzyme-Linked Immunosorbent Assay) kit is an in vitro enzyme-linked immunosorbent assay for the quantitative measurement of human GM-CSF in serum, plasma, cell culture supernatants and urine.
Immunogen
Recombinant Human GM-CSF
Other Notes
A sample Certificate of Analysis is available for this product.
Please type the word sample in the text box provided for lot number.
Please type the word sample in the text box provided for lot number.
signalword
Warning
hcodes
pcodes
Hazard Classifications
Met. Corr. 1
存储类别
8B - Non-combustible corrosive hazardous materials
flash_point_f
Not applicable
flash_point_c
Not applicable
法规信息
常规特殊物品
低风险生物材料
此项目有
Rapamycin inhibits GM-CSF-induced neutrophil migration.
Gomez-Cambronero J
Febs Letters (2003)
D Margriet Ouwens et al.
Diabetologia, 57(10), 2208-2214 (2014-07-19)
Type 1 diabetes is associated with moderate cognitive decline and cerebral alterations and may lead to an increased risk of dementia, including Alzheimer's disease. This study aimed to investigate the levels of risk markers for Alzheimer's disease in middle-aged patients
Role of toll-like receptor 2 (TLR2) in neutrophil activation: GM-CSF enhances TLR2 expression and TLR2-mediated interleukin 8 responses in neutrophils.
Blood (2002)
Agnieszka Swierczak et al.
Cancer immunology research, 2(8), 765-776 (2014-07-10)
Treatment options are limited for patients with breast cancer presenting with metastatic disease. Targeting of tumor-associated macrophages through the inhibition of colony-stimulating factor-1 receptor (CSF-1R), a key macrophage signaling pathway, has been reported to reduce tumor growth and metastasis, and
GM-CSF in inflammation and autoimmunity.
Hamilton JA
Trends in Immunology (2002)
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