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安全信息

RAB0082

Sigma-Aldrich

Human CD163 ELISA Kit

for serum, plasma, cell culture supernatant and urine

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About This Item

UNSPSC代码:
41116158
NACRES:
NA.32

种属反应性

human

包装

kit of 96 wells (12 strips x 8 wells)

技术

ELISA: suitable
capture ELISA: suitable

输入

sample type plasma
sample type cell culture supernatant(s)
sample type urine
sample type serum

assay range

inter-assay cv: <12%
intra-assay cv: <10%
sensitivity: 30 pg/mL
standard curve range: 32.77-8000 pg/mL

检测方法

colorimetric

运输

wet ice

储存温度

−20°C

基因信息

human ... CD163(9332)

一般描述

The Human CD163 (also known as hemoglobin scavenger receptor) ELISA (Enzyme-Linked Immunosorbent Assay) kit is an in vitro enzyme-linked immunosorbent assay for the quantitative measurement of human CD163 in serum, plasma, cell culture supernatants and urine.

免疫原

Recombinant Human CD163

应用

For research use only. Not for use in diagnostic procedures.
Please refer to the attached General ELISA KIT Procedure (sandwich, competitive & Indirect ELISA)
Human CD163 ELISA kit has been used to measure the levels of CD163 in plasma samples and cell culture supernatants.

生化/生理作用

Cluster of differentiation 163 (CD163) is a scavenger receptor. It is expressed on the surface of activated macrophages. This protein modulates anti-inflammatory functions and has a role in hemoglobin-haptoglobin clearance. Various cytokines influence the expression of CD163. It may be associated with hepatocellular carcinoma.

其他说明

A sample Certificate of Analysis is available for this product.
Please type the word sample in the text box provided for lot number.

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产品编号
说明
化学品安全说明书

  • RABELADAELISA 1X Assay/Sample Diluent Buffer A (Item D1)化学品安全说明书

  • RABELADBELISA 5X Assay/Sample Diluent Buffer B (Item E1)化学品安全说明书

  • RABSTOP3ELISA Stop Solution (Item I)化学品安全说明书

  • RABTMB3ELISA Colorimetric TMB Reagent (HRP Substrate, Item H)化学品安全说明书

  • RABWASH420X Wash Buffer (Item B)化学品安全说明书

象形图

Corrosion

警示用语:

Warning

危险声明

预防措施声明

危险分类

Met. Corr. 1

储存分类代码

8A - Combustible corrosive hazardous materials

法规信息

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Monocyte-lymphocyte cross-communication via soluble CD163 directly links innate immune system activation and adaptive immune system suppression following ischemic stroke
Grant C
Scientific Reports (2017)
Martin Hoenigl et al.
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 69(4), 676-686 (2018-11-13)
Despite effective antiretroviral therapy (ART), human immunodeficiency virus (HIV) infection remains associated with higher morbidity and mortality, driven, in part, by increased inflammation. Our objective was to identify associations between levels of plasma biomarkers of chronic inflammation, microbial translocation, and
A Ross Eckard et al.
HIV medicine, 15(9), 537-546 (2014-03-22)
HIV-infected patients on antiretroviral therapy (ART) have an increased cardiovascular disease (CVD) risk as a result of heightened inflammation and immune activation, despite at times having normal lipids and few traditional risk factors. Biomarkers are needed to identify such patients
Clinical significance of soluble CD163 in polymyositis-related or dermatomyositis-related interstitial lung disease.
Enomoto Y
Arthritis Research & Therapy (2017)
Grant C O'Connell et al.
Scientific reports, 7(1), 12940-12940 (2017-10-13)
CD163 is a scavenger receptor expressed on innate immune cell populations which can be shed from the plasma membrane via the metalloprotease ADAM17 to generate a soluble peptide with lympho-inhibitory properties. The purpose of this study was to investigate CD163

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