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安全信息

RAB0053

Sigma-Aldrich

小鼠MIP-3 β  / CCL19 ELISA试剂盒

for serum, plasma and cell culture supernatant

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别名:
C-C motif chemokine 19, CCL19, MIP-3 beta
UNSPSC代码:
41116158
NACRES:
NA.32

种属反应性

mouse

包装

kit of 96 wells (12 strips x 8 wells)

技术

ELISA: suitable
capture ELISA: suitable

输入

sample type serum
sample type cell culture supernatant(s)
sample type plasma

assay range

inter-assay cv: <12%
intra-assay cv: <10%
sensitivity: 5 pg/mL
standard curve range: 4.1-1000 pg/mL

检测方法

colorimetric

运输

wet ice

储存温度

−20°C

基因信息

mouse ... Ccl19(24047)

相关类别

一般描述

C-C motif chemokine ligand 19 (CCL19), also known as macrophage inflammatory protein (MIP)-3β, is encoded by the gene mapped to human chromosome 9. The encoded protein is specifically expressed in lymphoid tissues.
The Mouse MIP-3-β (Macrophage Inflammatory Protein 3 β) ELISA (Enzyme-Linked Immunosorbent Assay) kit is an in vitro enzyme-linked immunosorbent assay for the quantitative measurement of mouse MIP-3- β in serum, plasma, cell culture supernatants and urine.

免疫原

Recombinant Mouse MIP-3 β

应用

请参考Protocol了解详情。

生化/生理作用

C-C motif chemokine ligand 19 (CCL19) acts as a chemoattractant for T and B lymphocytes, dendritic cells, macrophage progenitor cells and natural killer cells. Therefore, this protein might play an essential role in migration of T cells in the thymus and transfer of T and B cells to secondary lymphoid organs. Overexpression of MIP-3 β (macrophage inflammatory protein-3β)/ C-C motif chemokine ligand 19 (CCL19) leads to pulmonary sarcoidosis.

其他说明

A sample Certificate of Analysis is available for this product.
Please type the word sample in the text box provided for lot number.

试剂盒组分也可单独购买

产品编号
说明
化学品安全说明书
  • RABELADEELISA 5X Assay/Sample Diluent Buffer E (Item E2)化学品安全说明书
  • RABSTOP3ELISA Stop Solution (Item I)化学品安全说明书
  • RABTMB3ELISA Colorimetric TMB Reagent (HRP Substrate, Item H)化学品安全说明书
  • RABWASH420X Wash Buffer (Item B)化学品安全说明书

象形图

Corrosion
GHS05

警示用语：

Warning

危险声明

H290

预防措施声明

P234 - P390

危险分类

Met. Corr. 1

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

法规信息

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访问文档库

CCL19 and CCL21 induce a potent proinflammatory differentiation program in licensed dendritic cells.
Marsland BJ
Immunity, 22(4), 493-505 (2005)
Expression of macrophage inflammatory protein-3 beta/CCL19 in pulmonary sarcoidosis.
Gibejova A
American Journal of Respiratory and Critical Care Medicine, 167(12), 1695-1703 (2003)
The CCR7 ligand elc (CCL19) is transcytosed in high endothelial venules and mediates T cell recruitment.
Baekkevold ES
The Journal of Experimental Medicine, 193(9), 1105-1112 (2001)

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