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种属反应性
mouse
包装
kit of 96 wells (12 strips x 8 wells)
技术
ELISA: suitable
capture ELISA: suitable
输入
sample type serum
sample type cell culture supernatant(s)
sample type plasma
assay range
inter-assay cv: <12%
intra-assay cv: <10%
sensitivity: 5 pg/mL
standard curve range: 4.1-1000 pg/mL
检测方法
colorimetric
运输
wet ice
储存温度
−20°C
基因信息
mouse ... Ccl19(24047)
一般描述
C-C motif chemokine ligand 19 (CCL19), also known as macrophage inflammatory protein (MIP)-3β, is encoded by the gene mapped to human chromosome 9. The encoded protein is specifically expressed in lymphoid tissues.
The Mouse MIP-3-β (Macrophage Inflammatory Protein 3 β) ELISA (Enzyme-Linked Immunosorbent Assay) kit is an in vitro enzyme-linked immunosorbent assay for the quantitative measurement of mouse MIP-3- β in serum, plasma, cell culture supernatants and urine.
免疫原
Recombinant Mouse MIP-3 β
应用
请参考Protocol了解详情。
生化/生理作用
C-C motif chemokine ligand 19 (CCL19) acts as a chemoattractant for T and B lymphocytes, dendritic cells, macrophage progenitor cells and natural killer cells. Therefore, this protein might play an essential role in migration of T cells in the thymus and transfer of T and B cells to secondary lymphoid organs. Overexpression of MIP-3 β (macrophage inflammatory protein-3β)/ C-C motif chemokine ligand 19 (CCL19) leads to pulmonary sarcoidosis.
其他说明
A sample Certificate of Analysis is available for this product.
Please type the word sample in the text box provided for lot number.
Please type the word sample in the text box provided for lot number.
警示用语：
Warning
危险声明
预防措施声明
危险分类
Met. Corr. 1
储存分类代码
8B - Non-combustible corrosive hazardous materials
闪点(°F)
Not applicable
闪点(°C)
Not applicable
法规信息
新产品
CCL19 and CCL21 induce a potent proinflammatory differentiation program in licensed dendritic cells.
Marsland BJ
Immunity, 22(4), 493-505 (2005)
The CCR7 ligand elc (CCL19) is transcytosed in high endothelial venules and mediates T cell recruitment.
Baekkevold ES
The Journal of Experimental Medicine, 193(9), 1105-1112 (2001)
Expression of macrophage inflammatory protein-3 beta/CCL19 in pulmonary sarcoidosis.
Gibejova A
American Journal of Respiratory and Critical Care Medicine, 167(12), 1695-1703 (2003)
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