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种属反应性
human
包装
kit of 96 wells (12 strips x 8 wells)
技术
ELISA: suitable
capture ELISA: suitable
输入
sample type serum
sample type cell culture supernatant(s)
sample type urine
sample type plasma
assay range
inter-assay cv: <12%
intra-assay cv: <10%
sensitivity: 45 pg/mL
standard curve range: 46.88-3000 pg/mL
检测方法
colorimetric
运输
wet ice
储存温度
−20°C
基因信息
human ... BMP2(650)
一般描述
BMP2（骨形态发生蛋白2）由位于人染色体20p12.3上的基因编码。 编码的蛋白质属于转化生长因子-β （TGFβ）超家族。BMP-2表达于心脏、肺和背主动脉中。
人 BMP2（骨形态发生蛋白2） ELISA（酶联免疫吸附测定）试剂盒采用体外酶联免疫吸附测定法，定量测定人血清、血浆、细胞培养物上清液和尿液中的BMP-2含量。
免疫原
重组人 BMP2
应用
仅供研究使用。不用于诊断操作。
人BMP2（骨形态发生蛋白2） ELISA试剂盒已被用于测量小鼠类器官条件培养基中BMP的浓度。
请参阅随附的常规ELISA试剂盒 操作步骤 （夹心、竞争性&和间接ELISA）
人BMP2（骨形态发生蛋白2） ELISA试剂盒已被用于测量小鼠类器官条件培养基中BMP的浓度。
请参阅随附的常规ELISA试剂盒 操作步骤 （夹心、竞争性&和间接ELISA）
生化/生理作用
BMP2（骨形态发生蛋白2）在自主神经系统谱系特异性碱性-螺旋-环-螺旋蛋白MASH1（哺乳动物无刚毛鳞甲同系物-1）的激活以及神经嵴干细胞的体外自主神经发生中具有至关重要的作用。在骨修复过程中，BMP-2控制Runt相关转录因子2（Runx2）和Osterix（Osx）的表达，从而增强间充质干细胞的迁移、增殖和成骨分化。 除了具有成骨活性外，BMP-2在心脏形态发生中也具有重要作用。重组人骨形态发生蛋白2（rhBMP-2）在口腔鳞状细胞癌的发病机理中具有至关重要的作用。BMP-2基因突变与骨质疏松症有关。
其他说明
本产品提供样本分析证书。
请在批号对应的文本框中输入单词 sample 。
请在批号对应的文本框中输入单词 sample 。
试剂盒组分也可单独购买
产品编号
说明
化学品安全说明书
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