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Merck
CN

RAB0028

Sigma-Aldrich

人BMP2 ELISA试剂盒

for serum, plasma, cell culture supernatant and urine

别名:

BMP-2, Bone morphogenetic protein 2

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About This Item

UNSPSC代码:
41116158
NACRES:
NA.32

种属反应性

human

包装

kit of 96 wells (12 strips x 8 wells)

技术

ELISA: suitable
capture ELISA: suitable

输入

sample type serum
sample type cell culture supernatant(s)
sample type urine
sample type plasma

assay range

inter-assay cv: <12%
intra-assay cv: <10%
sensitivity: 45 pg/mL
standard curve range: 46.88-3000 pg/mL

检测方法

colorimetric

运输

wet ice

储存温度

−20°C

基因信息

human ... BMP2(650)

一般描述

BMP2(骨形态发生蛋白2)由位于人染色体20p12.3上的基因编码。 编码的蛋白质属于转化生长因子-β (TGFβ)超家族。BMP-2表达于心脏、肺和背主动脉中。
人 BMP2(骨形态发生蛋白2) ELISA(酶联免疫吸附测定)试剂盒采用体外酶联免疫吸附测定法,定量测定人血清、血浆、细胞培养物上清液和尿液中的BMP-2含量。

免疫原

重组人 BMP2

应用

仅供研究使用。不用于诊断操作。
人BMP2(骨形态发生蛋白2) ELISA试剂盒已被用于测量小鼠类器官条件培养基中BMP的浓度。
请参阅随附的常规ELISA试剂盒 操作步骤 (夹心、竞争性&和间接ELISA)

生化/生理作用

BMP2(骨形态发生蛋白2)在自主神经系统谱系特异性碱性-螺旋-环-螺旋蛋白MASH1(哺乳动物无刚毛鳞甲同系物-1)的激活以及神经嵴干细胞的体外自主神经发生中具有至关重要的作用。在骨修复过程中,BMP-2控制Runt相关转录因子2(Runx2)和Osterix(Osx)的表达,从而增强间充质干细胞的迁移、增殖和成骨分化。 除了具有成骨活性外,BMP-2在心脏形态发生中也具有重要作用。重组人骨形态发生蛋白2(rhBMP-2)在口腔鳞状细胞癌的发病机理中具有至关重要的作用。BMP-2基因突变与骨质疏松症有关。

其他说明

本产品提供样本分析证书。
请在批号对应的文本框中输入单词 sample

试剂盒组分也可单独购买

产品编号
说明
化学品安全说明书

  • RABELADAELISA 1X Assay/Sample Diluent Buffer A (Item D1)化学品安全说明书

  • RABELADBELISA 5X Assay/Sample Diluent Buffer B (Item E1)化学品安全说明书

  • RABSTOP3ELISA Stop Solution (Item I)化学品安全说明书

  • RABTMB3ELISA Colorimetric TMB Reagent (HRP Substrate, Item H)化学品安全说明书

  • RABWASH420X Wash Buffer (Item B)化学品安全说明书

象形图

Corrosion

警示用语:

Warning

危险声明

预防措施声明

危险分类

Met. Corr. 1

储存分类代码

8A - Combustible corrosive hazardous materials

法规信息

常规特殊物品

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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访问文档库

R E De la Vega et al.
European cells & materials, 40, 160-171 (2020-10-07)
There is much interest in understanding the influence of the immune system on bone healing, including a number of reports suggesting a beneficial effect of FK506 (tacrolimus) in this regard. The influence of FK506 in a rat, femoral, critical size
Tadashi Ninomiya et al.
Cell transplantation, 23(6), 691-701 (2013-02-12)
Regeneration of alveolar bone is critical for the successful treatment of periodontal diseases. The periodontal ligament (PDL) has been widely investigated as a source of cells for the regeneration of periodontal tissues. In the present study where we attempted to
Yingnan Geng et al.
Communications biology, 4(1), 82-82 (2021-01-21)
Bone has a remarkable potential for self-healing and repair, yet several injury types are non-healing even after surgical or non-surgical treatment. Regenerative therapies that induce bone repair or improve the rate of recovery are being intensely investigated. Here, we probed
Khaled Waleed Zaid et al.
Asian Pacific journal of cancer prevention : APJCP, 17(3), 927-932 (2016-04-05)
Bone morphogenetic proteins (BMPs), belonging to the transforming growth factor-β superfamily, regulate many cellular activities including cell migration, differentiation, adhesion, proliferation and apoptosis. Use of recombinant human bone morphogenic protein?2 (rhBMP?2) in oral and maxillofacial surgery has seen a tremendous
Unnur Styrkarsdottir et al.
PLoS biology, 1(3), E69-E69 (2003-12-24)
Osteoporotic fractures are a major cause of morbidity and mortality in ageing populations. Osteoporosis, defined as low bone mineral density (BMD) and associated fractures, have significant genetic components that are largely unknown. Linkage analysis in a large number of extended

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