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种属反应性
rat, mouse, human
包装
kit of 96 wells (12 strips x 8 wells)
技术
ELISA: suitable
enzyme immunoassay: suitable
输入
sample type cell lysate
sample type plasma
sample type serum
sample type culture supernatant(s)
assay range
inter-assay cv: <15%
intra-assay cv: <10%
sensitivity: 5.84 pg/mL
standard curve range: 0.1-1000 ng/mL
检测方法
colorimetric
运输
wet ice
储存温度
−20°C
基因信息
human ... APLN(8862)
一般描述
Apelin C末端酶免疫测定（EIA）试剂盒是一种基于竞争性酶免疫测定原理，对Apelin C末端肽进行体外定量测定的方法。 EIA-APC-1试剂盒可检测所有活性Apelin肽，包括Apelin-13、Apelin-28、Apelin-31和Apelin-36。
免疫原
Apelin，合成肽
应用
仅供研究使用。不可用于诊断过程。
Apelin EIA试剂盒已被用于确定脂肪前细胞生长培养基中apelin的浓度。
Apelin EIA试剂盒已被用于确定脂肪前细胞生长培养基中apelin的浓度。
生化/生理作用
Apelin（APLN）由白色脂肪组织分泌。它是一种在肿瘤细胞进程和血管形成中起作用的脂肪因子。该蛋白可能在肥胖相关疾病中起作用。APLN可参与调节能量稳态、水平衡、葡萄糖代谢和免疫力。它在许多癌症中显示出上调。
Apelin Attenuates Oxidative Stress in Human Adipocytes*
Aung Than
The Journal of Biological Chemistry (2014)
Bogusz Trojanowicz et al.
Toxins, 12(12) (2020-12-02)
Apelin peptides (APLN) serve as second substrates for angiotensin-converting enzyme 2 (ACE2) and, in contrast to angiotensin II (AngII), exert blood-pressure lowering and vasodilatation effects through binding to G-coupled APLN receptor (APLNR). ACE2-mediated cleavage of the APLN may reduce its
Serum apelin levels and body composition changes in breast cancer patients treated with an aromatase inhibitor.
Salman T
Journal of B.U.ON. : Official Journal of the Balkan Union of Oncology (2016)
Assessment of Apelin Serum Levels in Persistent Atrial Fibrillation and Coronary Artery Disease.
Riazian M
The American Journal of the Medical Sciences (2016)
Search for Genetic Variant in the Apelin Gene by Resequencing and Association Study in European Subjects.
Sentinelli F
Genetic Testing and Molecular Biomarkers (2016)
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