R7882
视黄醇乙酸酯
solid or viscous liquid, BioReagent, synthetic, suitable for cell culture
别名:
维生素 A 醋酸酯, 醋酸维生素 A
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关于此项目
经验公式（希尔记法）:
C22H32O2
化学文摘社编号:
分子量:
328.49
NACRES:
NA.75
PubChem Substance ID:
eCl@ss:
34058009
UNSPSC Code:
12352205
EC Number:
204-844-2
MDL number:
Beilstein/REAXYS Number:
1915439
Assay:
≥90% (HPLC)
Form:
solid or viscous liquid
InChI key
QGNJRVVDBSJHIZ-QHLGVNSISA-N
InChI
1S/C22H32O2/c1-17(9-7-10-18(2)14-16-24-20(4)23)12-13-21-19(3)11-8-15-22(21,5)6/h7,9-10,12-14H,8,11,15-16H2,1-6H3/b10-7+,13-12+,17-9+,18-14+
SMILES string
CC1=C(/C=C/C(C)=C/C=C/C(C)=C/COC(C)=O)C(C)(C)CCC1
biological source
synthetic
product line
BioReagent
assay
≥90% (HPLC)
form
solid or viscous liquid
potency
~2,800,000 I.U. per g
mol wt
Mw 328.49 g/mol
technique(s)
cell culture | mammalian: suitable
color
light yellow to dark yellow
mp
57-58 °C
solubility
absolute ethanol: 25 mg/mL (lit.)
storage temp.
−20°C
Quality Level
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General description
视黄醇乙酸酯是维生素A的天然酯衍生物。 它可用于M-199、NCTC-109和William′培养基等经典培养基。维生素A是血清的一种成分，可用于大多数具有一定维生素A水平的含血清细胞培养系统。
Application
视黄醇乙酸酯已被用作高效液相色谱分析（HPLC）中测量维生素C浓度的标准品，并可用作制备完整培养基的补充剂。
Biochem/physiol Actions
视黄酸是视黄醇的氧化形式，其对于上皮细胞和相关细胞类型（尤其是神经细胞）具有激素样生长因子和分化活性。视黄酸可诱导胚胎干细胞成为神经细胞。现已确知视黄醇乙酸酯可有效治疗乳腺癌。
Preparation Note
这种材料的熔点约为58°C。为了便于包装，其已被熔化并以结晶固体或过冷粘稠液体的形式存在。
Other Notes
全反式
signalword
Danger
hcodes
Hazard Classifications
Aquatic Chronic 4 - Repr. 1B
存储类别
6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
wgk
WGK 2
ppe
Eyeshields, Gloves, type ABEK (EN14387) respirator filter
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Mi JD, et al.
Journal of Dairy Science, 99(1), 818-824 (2016)
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Asian-Australasian journal of animal sciences, 33(5), 742-752 (2020-02-15)
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Ortega F, et al.
Nature Protocols, 6(12), 1847-1847 (2011)
Natalia Cernicchiaro et al.
Foodborne pathogens and disease, 7(9), 1071-1081 (2010-05-27)
Alteration of the gastro-intestinal tract through manipulation of cattle diets has been proposed as a preharvest control measure to reduce fecal shedding of Escherichia coli O157:H7. The objective of this study was to examine the effects of the energy source's
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