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R5155

Sigma-Aldrich

罗库溴铵 溴化物

≥97% (perchloric acid titration)

别名:

(+)-Rocuronium bromide

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About This Item

经验公式（希尔记法）:
C32H53BrN2O4
CAS号:
119302-91-9
分子量:
609.68
MDL编号:
MFCD00867768
UNSPSC代码:
51152000
PubChem化学物质编号:
329824032
NACRES:
NA.77

质量水平

100

方案

≥97% (perchloric acid titration)

表单

powder

官能团

ester

运输

ambient

储存温度

room temp

SMILES字符串

[Br-].CC(=O)O[C@H]1[C@H](C[C@H]2[C@@H]3CC[C@H]4C[C@H](O)[C@H](C[C@]4(C)[C@H]3CC[C@]12C)N5CCOCC5)[N+]6(CCCC6)CC=C

InChI

1S/C32H53N2O4.BrH/c1-5-14-34(15-6-7-16-34)28-20-26-24-9-8-23-19-29(36)27(33-12-17-37-18-13-33)21-32(23,4)25(24)10-11-31(26,3)30(28)38-22(2)35;/h5,23-30,36H,1,6-21H2,2-4H3;1H/q+1;/p-1/t23-,24+,25-,26-,27-,28-,29-,30-,31-,32-;/m0./s1

InChI key

OYTJKRAYGYRUJK-FMCCZJBLSA-M

基因信息

human ... CHRNA1(1134) , CHRNB1(1140) , CHRND(1144) , CHRNE(1145) , CHRNG(1146)

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相关类别

生化/生理作用

Aminosteroid; neuromuscular blocker for anaesthesia
Rocuronium Bromide is a fumarate, non-depolarizing, neuromuscular blocking agent. It is rapid-acting, relaxes the skeletal muscle and decreases oxygen consumption during surgery. It competes with acetylcholine and bind to cholinergic receptors at neuromuscular junctions.

制备说明

Rocuronium bromide yields clear, light yellow solution in water at 100 mg/ml.

象形图

Skull and crossbones
GHS06

警示用语：

Danger

危险声明

H301,H335

危险分类

Acute Tox. 3 Oral - STOT SE 3

靶器官

Respiratory system

储存分类代码

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

个人防护装备

Eyeshields, Gloves, type N95 (US)

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number
BCCJ2834
BCCD9443
BCCD4115
BCCB8512
BCBP8416V

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Adrienn Pongrácz et al.
Anesthesiology, 119(1), 36-42 (2013-05-15)
Doses of sugammadex required to reverse deep, moderate, and shallow rocuronium-induced neuromuscular blockade have been established. However, no adequate doses for the reversal of reappearance of four twitches of train-of-four (TOF) stimulation (threshold TOF-count-four) have been established. This single-center, randomized
Yuji Kadoi et al.
The journal of ECT, 29(1), 33-36 (2012-10-12)
This study was conducted to (1) compare the recovery times from rocuronium-induced muscle relaxation after reversal with sugammadex between young and elderly patients undergoing electroconvulsive therapy (ECT), and (2) to examine the existence of a correlation between cardiac index and
Amelia Pickard et al.
Paediatric anaesthesia, 23(9), 871-873 (2013-06-15)
Myotonic dystrophy type 1 (MD1) is the commonest muscular dystrophy found in adults; however, it may present in the neonatal period with hypotonia, talipes, poor feeding, and respiratory failure. Inheritance is autosomal dominant with a defect in the DMPK gene
Mats Eriksson et al.
Clinical laboratory, 61(7), 825-829 (2015-08-25)
Determination of troponin I may be important in the management of the critically ill patient. In medical emergencies, especially when vascular access is difficult to achieve, the use of intraosseous (10) needles is recommended. We aimed to perform a descriptive
Shana L Ballow et al.
The journal of trauma and acute care surgery, 73(6), 1401-1405 (2012-11-29)
In the emergency department (ED) of a teaching hospital, rapid sequence intubation (RSI) is performed by physicians with a wide range of experience. A variety of medications have been used for RSI, with potential for inadequate or excessive dosing as
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