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Merck
CN

R3150

Sigma-Aldrich

Monoclonal Anti-RhoGAP (p190) antibody produced in mouse

clone D2D6, purified immunoglobulin, buffered aqueous solution

别名:

Anti-GRLF1, Anti-Glucorticoid Receptor Binding Factor 1, Anti-p190

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About This Item

MDL编号:
UNSPSC代码:
12352203
NACRES:
NA.41

生物来源

mouse

质量水平

偶联物

unconjugated

抗体形式

purified immunoglobulin

抗体产品类型

primary antibodies

克隆

D2D6, monoclonal

表单

buffered aqueous solution

分子量

antigen ~190 kDa

种属反应性

mouse, rat, monkey, human

技术

immunoprecipitation (IP): 4 μg using 500 μg of a human A431 cell RIPA lysate
western blot: 0.5-2 μg/mL using RIPA lysates from human A431 cells

同位素/亚型

IgG

运输

dry ice

储存温度

−20°C

靶向翻译后修饰

unmodified

基因信息

human ... GRLF1(2909)
mouse ... Grlf1(232906)
rat ... Grlf1(306400)

免疫原

GST fusion protein corresponding to amino acids 180-610 of rat p190 RhoGAP.

其他说明

RhoGAP appears to couple signal transduction via Ras and Rho through its association with RasGAP.

外形

Solution in 0.1 M Tris-glycine, pH 7.4, containing 0.15 sodium chloride and 0.05% sodium azide.

制备说明

Purified using protein G.

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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储存分类代码

10 - Combustible liquids

WGK

nwg

闪点(°F)

Not applicable

闪点(°C)

Not applicable

法规信息

新产品

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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访问文档库

Brajendra K Tripathi et al.
The Journal of cell biology, 218(9), 3060-3076 (2019-07-17)
SRC and ERK kinases control many cell biological processes that promote tumorigenesis by altering the activity of oncogenic and tumor suppressor proteins. We identify here a physiological interaction between DLC1, a focal adhesion protein and tumor suppressor, with SRC and

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