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生物来源
human
质量水平
重组
expressed in E. coli
检测方案
>95% (SDS-PAGE)
形式
lyophilized powder
分子量
(Contains two disulfide-linked subunits: A chain ~2.8 kDa B chain ~3.3 kDa)
技术
cell culture | mammalian: suitable
适用性
endotoxin tested
UniProt登记号
储存温度
−20°C
基因信息
human ... RLN1(6013)
一般描述
Cell signaling hormone that is prominent in the prostate, and belongs to the insulin superfamily
生化/生理作用
Relaxin 1 may function in regulating blood pressure, controlling heart rate, and releasing oxytocin and vasopressin
Relaxin has been shown to have antifibrotic effects in renal fibroblasts through mechanisms that increase collagenase activity and via TGF-β signaling.
外形
Lyophilized powder containing BSA
重悬
In Phosphate buffered saline solution containing at least 0.1% serum albumin. The concentration should be ≥10 μg/mL
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
法规信息
新产品
Rosemary Masterson et al.
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, 19(3), 544-552 (2004-02-10)
Renal fibroblasts are important effector cells in tubulointerstitial fibrosis, with experimental antifibrotic strategies focusing on the functional down-regulation of these cells. Several experimental models of fibrosis have provided evidence for the effectiveness of the polypeptide hormone relaxin as a potential
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