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Merck
CN

R0656

Sigma-Aldrich

Anti-Rab14 (C-terminal) antibody produced in rabbit

~1.0 mg/mL, affinity isolated antibody, buffered aqueous solution

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别名:
Anti-F protein-binding protein 1, Anti-GTPase Rab14, Anti-RAB14, member RAS oncogene family, Anti-Small GTP binding protein RAB14
UNSPSC代码:
12352203
NACRES:
NA.41

生物来源

rabbit

质量水平

偶联物

unconjugated

抗体形式

affinity isolated antibody

抗体产品类型

primary antibodies

克隆

polyclonal

形式

buffered aqueous solution

分子量

antigen ~24 kDa

种属反应性

mouse, human, rat

浓度

~1.0 mg/mL

技术

immunoprecipitation (IP): 5-10 μg using whole extract of human Raji cells
indirect immunofluorescence: 2.5-5 μg/mL using rat NRK cells fixed and permeabilized with 4% paraformaldehyde followed by 0.4% saponin
western blot: 1-2 μg/mL using whole extract of mouse brain

UniProt登记号

运输

dry ice

储存温度

−20°C

靶向翻译后修饰

unmodified

基因信息

human ... RAB14(51552)
mouse ... Rab14(68365)
rat ... Rab14(94197)

一般描述

Rab14 (Ras-related protein) is a Golgi-related Rab, that is located on chromosome 9q33.2. It is present in the endo-lysosomal pathway and contractile vacuole system of membranes. It is expressed almost in all tissues.
Rab14 (Ras-related protein) is a member of the Rab family of small guanosine triphosphatases (GTPases).

应用

Anti-Rab14 (C-terminal) antibody produced in rabbit has been used in:immunoblotting, immunoprecipitation, indirect immunofluorescence.

生化/生理作用

Rab14 (Ras-related protein) participates in membrane trafficking between the Golgi complex and endosomes. It may play an important role in surfactant secretion.

外形

0.01M 磷酸缓冲盐溶液,pH 7.4,含 15mM 叠氮化钠。

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

WGK

WGK 2

闪点(°F)

Not applicable

闪点(°C)

Not applicable

个人防护装备

Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)

法规信息

常规特殊物品

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Annexin A2 interactions with Rab14 in alveolar type II cells
Gou D, et al.
The Journal of Biological Chemistry, 283(19), 13156-13164 (2008)
RabD, a Dictyostelium Rab14-related GTPase, regulates phagocytosis and homotypic phagosome and lysosome fusion
Harris E and Cardelli J
Journal of Cell Science, 115(Pt 18), 3703-3713 (2002)
The functions of Rab GTPases in plant membrane traffic
Woollard AAD and Moore I
Current Opinion in Plant Biology, 11(6), 610-619 (2008)
A Lacoma et al.
Virulence, 8(8), 1761-1775 (2017-08-02)
Staphylococcus aureus is a particularly difficult pathogen to eradicate from the respiratory tract. Previous studies have highlighted the intracellular capacity of S.aureus in several phagocytic and non-phagocytic cells. The aim of this study was to define S.aureus interaction within a
A large-scale rheumatoid arthritis genetic study identifies association at chromosome 9q33.2
Chang M, et al.
PLoS Genetics, 4(6) (2008)

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