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Q3638

Sigma-Aldrich

喹硫平 半富马酸盐

≥98% (HPLC)

别名:

2-[2-（4-二苯并[b，f] [1,4]硫氮杂-11-基-1-哌嗪基）乙氧基]乙醇半富马酸盐, 喹硫平富马酸盐

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About This Item

经验公式（希尔记法）:
C21H25N3O2S · 0.5C4H4O4
CAS号:
111974-72-2
分子量:
441.54
MDL编号:
MFCD03423782
UNSPSC代码:
12352200
PubChem化学物质编号:
329823864
NACRES:
NA.77

质量水平

100

方案

≥98% (HPLC)

表单

powder

储存条件

desiccated

颜色

white to off-white

溶解性

DMSO: >10 mg/mL

创始人

AstraZeneca

储存温度

2-8°C

SMILES字符串

OC(=O)\C=C\C(O)=O.OCCOCCN1CCN(CC1)C2=Nc3ccccc3Sc4ccccc24.OCCOCCN5CCN(CC5)C6=Nc7ccccc7Sc8ccccc68

InChI

1S/2C21H25N3O2S.C4H4O4/c2*25-14-16-26-15-13-23-9-11-24(12-10-23)21-17-5-1-3-7-19(17)27-20-8-4-2-6-18(20)22-21;5-3(6)1-2-4(7)8/h2*1-8,25H,9-16H2;1-2H,(H,5,6)(H,7,8)/b;;2-1+

InChI key

ZTHJULTYCAQOIJ-WXXKFALUSA-N

基因信息

human ... DRD2(1813) , HTR2A(3356) , HTR2C(3358)

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一般描述

喹硫平是一种二苯并硫氮杂卓衍生物，也称为舍罗库尔和氯马斯汀。

应用

喹硫平半富马酸盐已被用作β-抑制蛋白2 突变体T205M 募集的拮抗剂。

生化/生理作用

喹硫平促进少突胶质细胞的体外形成。它用于治疗抑郁症。
喹硫平半富马酸盐是一种联合血清素（5HT2）和多巴胺（D2）受体拮抗剂。
喹硫平半富马酸盐是一种非典型抗精神病药，一种联合血清素（5HT2）和多巴胺（D2）受体拮抗剂。

特点和优势

《受体分类和信号转导》手册的多巴胺受体页有该化合物的介绍。想要浏览手册的其他页面， 请单击此处。
该化合物由AstraZeneca开发。要浏览其他药物开发化合物和批准的药物/候选药物列表，单击此处。

象形图

Exclamation markEnvironment
GHS07,GHS09

警示用语：

Warning

危险声明

H302,H400

预防措施声明

P273 - P301 + P312 + P330

危险分类

Acute Tox. 4 Oral - Aquatic Acute 1

储存分类代码

11 - Combustible Solids

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number
0000414432
0000414432
0000017823
0000233388
0000017823

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