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Merck
CN

Q104

Sigma-Aldrich

喹啉酸

别名:

2,3-Pyridinedicarboxylic acid

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About This Item

经验公式(希尔记法):
C7H5NO4
CAS号:
分子量:
167.12
Beilstein:
137110
EC 号:
MDL编号:
UNSPSC代码:
12352200
PubChem化学物质编号:

SMILES字符串

OC(=O)c1cccnc1C(O)=O

InChI

1S/C7H5NO4/c9-6(10)4-2-1-3-8-5(4)7(11)12/h1-3H,(H,9,10)(H,11,12)

InChI key

GJAWHXHKYYXBSV-UHFFFAOYSA-N

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说明
价格

象形图

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警示用语:

Warning

危险声明

预防措施声明

危险分类

Eye Irrit. 2 - STOT SE 3

靶器官

Respiratory system

储存分类代码

13 - Non Combustible Solids

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

个人防护装备

dust mask type N95 (US), Eyeshields, Gloves

法规信息

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Gilles J Guillemin et al.
Neuro-degenerative diseases, 2(3-4), 166-176 (2006-08-16)
The kynurenine pathway (KP) is a major route of L-tryptophan catabolism leading to production of several neurobiologically active molecules. Among them is the excitotoxin quinolinic acid (QUIN) that is known to be involved in the pathogenesis of several major inflammatory
Valéry Combes et al.
Trends in parasitology, 28(8), 311-319 (2012-06-26)
Homeostasis implies constant operational defence mechanisms, against both external and internal threats. Infectious agents are prominent among such threats. During infection, the host elicits the release of a vast array of molecules and numerous cell-cell interactions are triggered. These pleiomorphic
Gilles J Guillemin
The FEBS journal, 279(8), 1356-1365 (2012-01-18)
Over the last two decades, evidence for the involvement of quinolinic acid (QUIN) in neuroinflammatory diseases has been exponentially increasing. Within the brain, QUIN is produced and released by infiltrating macrophages and activated microglia, the very cells that are prominent
Apsara Kandanearatchi et al.
The FEBS journal, 279(8), 1366-1374 (2012-01-21)
This brief review will first consider HIV associated neurocognitive disorder followed by the current understanding of its neuropathogenesis. Against this background the role of the kynurenine pathway will be detailed. Evidence both direct and indirect will be discussed for involvement
F Moroni et al.
Journal of neurochemistry, 47(6), 1667-1671 (1986-12-01)
Quinolinic acid (QUIN), an excitotoxic tryptophan metabolite, has been identified and measured in human cerebrospinal fluid (CSF) using a mass-fragmentographic method. Furthermore, its content has been evaluated in frontal cortex obtained at autopsy from the cadavers of patients who died

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