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Merck
CN
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主要文件

PZ0315

Sigma-Aldrich

芦平曲韦

≥98% (HPLC)

别名:

AG-7088, AG7088, 乙基 (E,4S)-4-[[(2R,5S)-2-[(4-氟苯基)甲基] -6-甲基-5-[(5-甲基-1,2-恶唑-3-羰基)氨基]-4-氧代庚酰基]氨基] -5-[(3S)-2-氧吡咯烷-3-基]戊-2-烯酸酯, 芦平曲韦

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About This Item

经验公式（希尔记法）:
C31H39FN4O7
CAS号:
223537-30-2
分子量:
598.66
UNSPSC代码:
12352200
NACRES:
NA.77

质量水平

100

方案

≥98% (HPLC)

表单

powder

旋光性

[α]/D +30 to +40°, c = 0.5 in chloroform-d

颜色

white to beige

溶解性

DMSO: 25 mg/mL, clear

储存温度

room temp

SMILES字符串

Fc1ccc(cc1)C[C@H](CC(=O)[C@@H](NC(=O)c3n[o]c(c3)C)C(C)C)C(=O)N[C@@H](C[C@@H]2CCNC2=O)\C=C\C(=O)OCC

InChI

1S/C31H39FN4O7/c1-5-42-27(38)11-10-24(16-21-12-13-33-29(21)39)34-30(40)22(15-20-6-8-23(32)9-7-20)17-26(37)28(18(2)3)35-31(41)25-14-19(4)43-36-25/h6-11,14,18,21-22,24,28H,5,12-13,15-17H2,1-4H3,(H,33,39)(H,34,40)(H,35,41)/b11-10+/t21-,22+,24+,28-/m0/s1

InChI key

CAYJBRBGZBCZKO-BHGBQCOSSA-N

一般描述

芦平曲韦是一种不可逆的拟肽抑制剂，其可靶向人鼻病毒（HRV）。其之前被命名为AG7088。芦平曲韦也被发现可能涉及 体外 抗病毒活性。

生化/生理作用

芦平曲韦（AG7088）是一种不可逆的人类鼻病毒（HRV）3C蛋白酶抑制剂，其也被发现可以抑制肠病毒和诺如病毒。

储存分类代码

11 - Combustible Solids

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

从最新的版本中选择一种：

分析证书(COA)

Lot/Batch Number
0000342480
0000342480
0000259144
0000259144
0000214988

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