PZ0129
CP-380736
≥98% (HPLC)
别名:
6,7-Bis(2-methoxyethoxy)-3,4-dihydroquinazolin-4-one, 6,7-Bis(2-methoxyethoxy)-4(3H)-quinazolinone, PF-00520893
登录 查看组织和合同定价。
选择尺寸
关于此项目
经验公式（希尔记法）:
C14H18N2O5
化学文摘社编号:
分子量:
294.30
NACRES:
NA.77
PubChem Substance ID:
UNSPSC Code:
51111800
MDL number:
产品名称
CP-380736, ≥98% (HPLC)
InChI key
PMQWTUWLIGJTQD-UHFFFAOYSA-N
SMILES string
COCCOc1cc2N=CNC(=O)c2cc1OCCOC
InChI
1S/C14H18N2O5/c1-18-3-5-20-12-7-10-11(15-9-16-14(10)17)8-13(12)21-6-4-19-2/h7-9H,3-6H2,1-2H3,(H,15,16,17)
assay
≥98% (HPLC)
form
powder
color
off-white to light tan
solubility
DMSO: ≥10 mg/mL
storage temp.
room temp
Quality Level
Biochem/physiol Actions
CP-380736 is an inhibitor of the epidermal growth factor receptor (EGFR). EGFR is a tyrosine kinase that activates MAPK, JNK, and Akt pathways, and is an important mediator of several types of cancer, including lung cancer and glioblastoma multiforme.
CP-380736 is selective inhibitor of epidermal growth factor receptor.
Features and Benefits
This compound is a featured product for Kinase Phosphatase Biology research. Click here to discover more featured Kinase Phosphatase Biology products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm.
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
Belén Sánchez-Maldonado et al.
Stem cells and development, 27(22), 1557-1576 (2018-09-27)
Cell spheroids are inducible or spontaneously generated cell aggregates produced in vitro that can provide a valuable model for developmental biology, stem cell biology, and cancer therapy research. This investigation aimed to define the cellular identity of spheroids spontaneously generated
商品
Our company offers many products related to EGFR for your research needs.
Discover Bioactive Small Molecules for Kinase Phosphatase Biology
我们的科学家团队拥有各种研究领域经验，包括生命科学、材料科学、化学合成、色谱、分析及许多其他领域.
联系客户支持