PZ0123
Avridine
≥97% (HPLC)
别名:
CP 20961, N,N-Dioctadecyl-N′,N′-bis(2-hydroxyethyl)-1,3-diaminopropane, N,N-Dioctadecyl-N′,N′-bis(2-hydroxyethyl)propanediamine
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关于此项目
经验公式（希尔记法）:
C43H90N2O2
化学文摘社编号:
分子量:
667.19
NACRES:
NA.77
PubChem Substance ID:
UNSPSC Code:
51111800
MDL number:
InChI key
WXNRAKRZUCLRBP-UHFFFAOYSA-N
SMILES string
CCCCCCCCCCCCCCCCCCN(CCCCCCCCCCCCCCCCCC)CCCN(CCO)CCO
InChI
1S/C43H90N2O2/c1-3-5-7-9-11-13-15-17-19-21-23-25-27-29-31-33-36-44(38-35-39-45(40-42-46)41-43-47)37-34-32-30-28-26-24-22-20-18-16-14-12-10-8-6-4-2/h46-47H,3-43H2,1-2H3
assay
≥97% (HPLC)
form
powder
color
white to off-white
solubility
DMSO: ≥5 mg/mL (with warming to 60 °C for 5 minutes)
storage temp.
room temp
Quality Level
Biochem/physiol Actions
Avridine is a potent synthetic adjuvant that can induce arthritis in most rat strains; immunomodulator and interferon-inducing.
存储类别
11 - Combustible Solids
flash_point_f
Not applicable
flash_point_c
Not applicable
Administration of intraliposomal CP20961 to mice activates peritoneal macrophages and augments serum antibody response to Toxoplasma gondii.
D Mack et al.
The Journal of eukaryotic microbiology, 41(5), 12S-12S (1994-09-01)
Chenguang Zhou et al.
Therapeutic delivery, 3(6), 715-723 (2012-07-31)
Lack of safe and efficient delivery of siRNA remains the greatest hurdle for the therapeutic application of siRNA. This article reports synthesis and evaluation of novel lipoidal amine-based nanocarrier (LANC) formulations for siRNA delivery. Physicochemical properties were analyzed for LANC
Comparative susceptibility of DA, LEW, and LEW.1AV1 rats to arthritis induced with different arthritogens: mineral oil, mycobacteria, muramyl dipeptide, avridine and rat collagen type II.
J C Lorentzen et al.
Transplantation proceedings, 29(3), 1692-1693 (1997-05-01)
S Tanaka et al.
International journal of immunopharmacology, 19(1), 15-24 (1997-01-01)
Dipeptidyl peptidase IV (DP IV, CD26) is a serine exoprotease which selectively cleaves the penultimate proline residue of polypeptides. This enzyme is also expressed as a surface marker on activated T cells. In order to assess the relevance of DP
A Berinstein et al.
Vaccine, 11(13), 1295-1301 (1993-10-01)
Foot-and-mouth disease is one of the more economically important diseases among meat-producing biungulate species. In contrast to natural infection, current foot-and-mouth disease virus (FMDV) vaccines, prepared with inactivated virus and adjuvants, elicit short-lived protection. The immunomodulating effect on FMDV vaccines
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