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COO原产地证书/COA分析证书

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PZ0035

Sutezolid

Name: Sutezolid
Brand: SIGMA

≥98% (HPLC)

别名:

(S)-N-[[3-[3-Fluoro-4-(4-thiomorpholinyl)phenyl]-2-oxo-5-oxazolidinyl]methyl]-acetamide, PNU-100480, PNU100480

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About This Item

经验公式（希尔记法）:

C₁₆H₂₀FN₃O₃S

CAS号:

168828-58-8

分子量:

353.41

MDL编号:

MFCD00937821

UNSPSC代码:

51111800

PubChem化学物质编号:

329823692

NACRES:

NA.77

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SML1581

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Y0002098

索拉非尼

质量水平

100

方案

≥98% (HPLC)

表单

powder

旋光性

[α]/D -8 to -12°, c = 1 in chloroform-d

颜色

white to beige

溶解性

DMSO: 20 mg/mL, clear

储存温度

room temp

SMILES字符串

FC1=CC(N(C[C@H](CNC(C)=O)O2)C2=O)=CC=C1N3CCSCC3

InChI

1S/C16H20FN3O3S/c1-11(21)18-9-13-10-20(16(22)23-13)12-2-3-15(14(17)8-12)19-4-6-24-7-5-19/h2-3,8,13H,4-7,9-10H2,1H3,(H,18,21)/t13-/m0/s1

InChI key

FNDDDNOJWPQCBZ-ZDUSSCGKSA-N

生化/生理作用

Sutezolid (PNU 100480) is an oxazolidinone antimicrobial. Sutezolid inhibits protein synthesis by inhibiting bacterial mRNA translation. Sutezolid is being investigated for the treatment of multiple drug–resistant and extensively drug-resistant tuberculosis. The compound is a less toxic and more potent derivative of linezolid.