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If you decide to place an order during this period, we reserve the right to adjust the price based on the evolving situation. We understand that market changes may cause inconvenience. We will negotiate with you if there’s a significant price fluctuation due to tariff policy changes before the order’s actual delivery, and in such cases we may adjust or cancel the order as necessary.

Merck
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PZ0015

Sigma-Aldrich

Trovafloxacin mesylate

>98% (HPLC), powder, Pannexin 1 inhibitor

别名:

(1α,5α,6α)-7-(6-Amino-3-azabicyclo[3.1.0]hex-3-yl)-1-(2,4-difluorophenyl)-6-fluoro-1,4-dihydro-4-oxo-1,8-naphthyridine-3-carboxylic acid methanesulfonate, CP-99219-27, Trovafloxacin methanesulfonate

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1 KIT
CN¥16,284.59

CN¥16,284.59

预计发货时间May 20, 2025详情

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1 KIT
CN¥16,284.59

About This Item

经验公式（希尔记法）:
C20H15F3N4O3 · CH3SO3H
CAS号:
147059-75-4
分子量:
512.46
MDL编号:
MFCD00913361
UNSPSC代码:
12352200
PubChem化学物质编号:
329823684
NACRES:
NA.77

CN¥16,284.59

预计发货时间May 20, 2025详情

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产品名称

Trovafloxacin mesylate, >98% (HPLC)

质量水平

100

方案

>98% (HPLC)

表单

powder

颜色

white to off-white

溶解性

DMSO: >10 mg/mL

储存温度

room temp

SMILES字符串

CS(O)(=O)=O.NC1C2CN(CC12)c3nc4N(C=C(C(O)=O)C(=O)c4cc3F)c5ccc(F)cc5F

InChI

1S/C20H15F3N4O3.CH4O3S/c21-8-1-2-15(13(22)3-8)27-7-12(20(29)30)17(28)9-4-14(23)19(25-18(9)27)26-5-10-11(6-26)16(10)24;1-5(2,3)4/h1-4,7,10-11,16H,5-6,24H2,(H,29,30);1H3,(H,2,3,4)/t10-,11+,16+;

InChI key

DYNZICQDCVYXFW-AHZSKCOESA-N

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Platinum wire reel, 1m, diameter 0.01mm, hard, 99.9%

GF29339286

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Platinum wire reel, 1m, diameter 0.25mm, hard, 99.95%

GF39961862

Platinum

assay

99.9%

assay

99.9%

assay

99.90%

assay

99.95%

manufacturer/tradename

Goodfellow 673-324-16

manufacturer/tradename

Goodfellow 620-377-72

manufacturer/tradename

Goodfellow 293-392-86

manufacturer/tradename

Goodfellow 399-618-62

form

wire

form

wire

form

wire

form

wire

mp

1772 °C (lit.)

mp

1772 °C (lit.)

mp

1772 °C (lit.)

mp

1772 °C (lit.)

density

21.45 g/cm3 (lit.)

density

21.45 g/cm3 (lit.)

density

21.45 g/cm3 (lit.)

density

21.45 g/cm3 (lit.)

bp

3827 °C (lit.)

bp

3827 °C (lit.)

bp

3827 °C (lit.)

bp

3827 °C (lit.)

应用

Trovafloxacin mesylate has been used as a test compound in toxicity assay to assess its toxicity in 2D hepatocyte cultures.[1] It has also been used to manipulate the mechanism of apoptotic cell disassembly during apoptosis.[2]

生化/生理作用

Trovafloxacin mesylate acts as a pannexin1 (Panx1) inhibitor.[2]
Trovafloxacin mesylate is a broad spectrum antibiotic.
Trovafloxacin mesylate is a broad spectrum antibiotic. Trovafloxacin mesylate blocks the activity of DNA gyrase and topoisomerase IV, enzymes essential in the repliction, transcription, and repair of bacterial DNA.

象形图

Health hazardCorrosion
GHS08,GHS05

警示用语：

Danger

危险声明

H314,H361

危险分类

Repr. 2 - Skin Corr. 1B

储存分类代码

8A - Combustible corrosive hazardous materials

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

    • 历史批次信息供参考:

    分析证书(COA)

    Lot/Batch Number
    020M4708V
    020M47081
    020M4708

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    Bioprinted 3D primary liver tissues allow assessment of organ-level response to clinical drug induced toxicity in vitro
    Nguyen DG, et al.
    PLoS ONE, 11(7), e0158674-e0158674 (2016)
    Determining the contents and cell origins of apoptotic bodies by flow cytometry
    Jiang L, et al.
    Scientific reports, 7(1), 14444-14444 (2017)
    Akira Nakajima et al.
    Cell biology and toxicology, 34(1), 65-77 (2017-03-13)
    Fluoroquinolones and propionic acid derivatives are widely used antibacterials and non-steroidal anti-inflammatory drugs, respectively, which have been reported to frequently trigger drug hypersensitivity reactions. Such reactions are induced by inflammatory mediators such as cytokines and chemokines. The present study investigated
    Jieyu Xu et al.
    Toxicology in vitro : an international journal published in association with BIBRA, 48, 286-301 (2018-02-07)
    Immortalized liver cells have been used for evaluating the toxicity of compounds; however, excessive glutathione is considered to lessen cytotoxicity. In this study, we compared the effects of glutathione depletion on cytotoxicities of drugs using HepaRG and HepG2 cells, which

    商品

    Bioactive Molecules for Immunology Research

    Bioactive small molecules for immune system signaling target identification/validation and antibiotics, antivirals, and antifungals offered.

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