质量水平
检测方案
≥98% (HPLC)
形式
powder
旋光性
[α]-15/D
颜色
white
溶解性
DMSO: >30 mg/mL
储存温度
room temp
SMILES字符串
CC(C)c1nnc(C)n1[C@H]2C[C@@H]3CC[C@H](C2)N3CC[C@H](NC(=O)C4CCC(F)(F)CC4)c5ccccc5
InChI
1S/C29H41F2N5O/c1-19(2)27-34-33-20(3)36(27)25-17-23-9-10-24(18-25)35(23)16-13-26(21-7-5-4-6-8-21)32-28(37)22-11-14-29(30,31)15-12-22/h4-8,19,22-26H,9-18H2,1-3H3,(H,32,37)/t23-,24+,25-,26-/m0/s1
InChI key
GSNHKUDZZFZSJB-QYOOZWMWSA-N
基因信息
human ... CCR5(1234)
WGK
WGK 1
闪点(°F)
Not applicable
闪点(°C)
Not applicable
The lancet. HIV, 1(2), e60-e67 (2015-10-02)
Immune reconstitution inflammatory syndrome (IRIS) is a common complication of antiretroviral therapy (ART) in patients with HIV. IRIS is associated with an increased risk of admission to hospital and death. We assessed whether CCR5 blockade with maraviroc reduces the risk
Assessment of the absorption, metabolism and absolute bioavailability of maraviroc in healthy male subjects
British Journal of Clinical Pharmacology, 65, 60-67 (2008)
Procoagulant and proinflammatory effects of red blood cells on lipopolysaccharide-stimulated monocytes
Journal of Thrombosis and Haemostasis, 13(9), 1676-1682 (2015)
The Journal of antimicrobial chemotherapy, 69(7), 1903-1910 (2014-03-22)
Non-alcoholic fatty liver disease (NAFLD) is the most common cause of chronic liver disease in the general population. The NAFLD spectrum ranges from simple steatosis to cirrhosis. The chemokine CCL5/RANTES plays an important role in the progression of hepatic inflammation
HIV-1 and SIV Infection Are Associated with Early Loss of Lung Interstitial CD4+ T Cells and Dissemination of Pulmonary Tuberculosis
Testing, 26(6), 1409-1418 (2019)
商品
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