生物来源
rabbit
质量水平
偶联物
unconjugated
抗体形式
affinity isolated antibody
抗体产品类型
primary antibodies
克隆
polyclonal
表单
buffered aqueous solution
种属反应性
rat, human, mouse
技术
immunofluorescence: suitable
immunohistochemistry: suitable
indirect ELISA: suitable
western blot: suitable
UniProt登记号
运输
dry ice
储存温度
−20°C
靶向翻译后修饰
unmodified
基因信息
human ... UNC93B1(81622)
一般描述
Unc93b (unc-93 homolog B1) is a multiple membrane-spanning protein, that is located in the endoplasmic reticulum. It is mainly present in the heart and also highly expressed in dendritic cells and macrophages. It is located on chromosome 11q13.
免疫原
a 19 amino acid peptide from near the amino-terminus of human Unc93b.
生化/生理作用
Unc93b (unc-93 homolog B1) plays an important role in controlling the activation of TLRs (toll-like receptors). It also participates in the localization of TLR3 (toll-like receptor 3) to the surface of cell.
联系
The action of this antibody can be blocked using blocking peptide SBP4553.
外形
Solution in phosphate buffered saline containing 0.02% sodium azide
免责声明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
未找到合适的产品？
试试我们的产品选型工具.
相关产品
储存分类代码
10 - Combustible liquids
WGK
WGK 2
闪点(°F)
Not applicable
闪点(°C)
Not applicable
法规信息
新产品
hUNC93B1: a novel human gene representing a new gene family and encoding an unc-93-like protein
Kashuba VI, et al.
Gene, 283(1-2), 209-217 (2002)
Assessing the function of human UNC-93B in Toll-like receptor signaling and major histocompatibility complex II response
Koehn J, et al.
Human immunology, 68(11), 871-878 (2007)
The role of UNC93B1 protein in surface localization of TLR3 receptor and in cell priming to nucleic acid agonists
Pohar J, et al.
The Journal of Biological Chemistry, 288(1), 442-454 (2013)
hUNC-93B1, a novel gene mainly expressed in the heart, is related to left ventricular diastolic function, heart failure morbidity and mortality in elderly men
Arnlov J, et al.
European Journal of Heart Failure, 7(6), 958-965 (2005)
Unc93B1 biases Toll-like receptor responses to nucleic acid in dendritic cells toward DNA- but against RNA-sensing
Fukui R, et al.
The Journal of Experimental Medicine, 206(6), 1339-1350 (2009)
我们的科学家团队拥有各种研究领域经验，包括生命科学、材料科学、化学合成、色谱、分析及许多其他领域.
联系技术服务部门